期刊著作

• Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2
  Nature Communications, 15, 1, 2024-12-01

• Dissociation of the nuclear WWOX/TRAF2 switch renders UV/cold shock-mediated nuclear bubbling cell death at low temperatures
  Cell Communication and Signaling, 22, 1, 2024-12-01
  [ Cold shock,Molecular switch,Signaling,TRAF2,UV,WWOX ]

• Investigation of the α9-nicotinic receptor single nucleotide polymorphisms induced oncogenic properties and molecular mechanisms in breast cancer
  Human Molecular Genetics, 33, 22, 1948-1965, 2024-11-08
  [ Breast cancer,Patient derived xenograft (PDX),Single-nucleotide polymorphisms (SNPs),Smoking exposure,α9-nicotinic acetylcholine receptor (α9-nAChR) ]

• Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent relapse and metastasis of triple-negative breast cancer
  Theranostics, 14, 5, 2167-2189, 2024-01-01
  [ CXCL7/CXCR2,IL-6/IL-6R,Immunotherapy,MCT-1,PD-L1 ]

• SCEL regulates switches between pro-survival and apoptosis of the TNF-α/TNFR1/NF-κB/c-FLIP axis to control lung colonization of triple negative breast cancer
  Journal of Biomedical Science, 30, 1, 2023-12-01
  [ Adalimumab,c-FLIP,Caspase 3,iTRAQ,mTNBC,NF-κB,SCEL,TNF-α,TNFR1 ]

• Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment
  Molecular Oncology, 17, 8, 1648-1665, 2023-08-01
  [ 8-isopentenylnaringenin,EGFR TKI acquired resistance,lung adenocarcinoma,necrosis,synergistic effects ]

• Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling
  Journal of Biomedical Science, 29, 1, 2022-12-22
  [ Cancer-associated fibroblast,Macrophages,Metastasis,NF-κB,Ovarian cancer,Periostin,TGF-β2 ]

• MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway
  Journal of Biomedical Science, 29, 1, 2022-12-01
  [ Cancer stemness,Chemoresistance,Dasatinib,Integrin β4,Keratin 17,miR-485-5p,Oral squamous cell carcinoma,β-catenin ]

• Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET
  Oncogene, 41, 7, 997-1010, 2022-02-11

• Nutrient supplements from selected botanicals mediated immune modulation of the tumor microenvironment and antitumor mechanism
  Cancer Immunology, Immunotherapy, 70, 12, 3435-3449, 2021-12-01
  [ Cancer immunotherapy,Immune modulating agents,MDSC,Nutrient supplement,TH1 ]

• Monocytes secrete CXCL7 to promote breast cancer progression
  Cell Death and Disease, 12, 12, 2021-12-01

• LOC550643, a Long Non-coding RNA, Acts as Novel Oncogene in Regulating Breast Cancer Growth and Metastasis
  Frontiers in Cell and Developmental Biology, 9, 2021-07-20
  [ breast cancer,lncRNA,metastasis,microRNA,ncRNA ]

• Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes
  Theranostics, 11, 15, 7527-7545, 2021-01-01
  [ Arginine starvation,cGAS-STING activation,DNA leakage,Epigenetic gene silencing ]

• Effects of synthetic glucocorticoids on breast cancer progression
  Steroids, 164, 2020-12-01
  [ Breast cancer,Glucocorticoids,Metastasis,microRNA-708,Rap1B ]

• DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits
  Oncogene, 39, 37, 5933-5949, 2020-09-10

• Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling
  Scientific Reports, 9, 1, 2019-12-01

• Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis
  EMBO Reports, 20, 10, 2019-10-04
  [ cystathionine gamma-lyase,hydrogen sulfide,IL-1beta,NF-kappaB,prostate cancer ]

• Cancer-derived VEGF-C increases chemokine production in lymphatic endothelial cells to promote CXCR2-dependent cancer invasion and MDSC recruitment
  Cancers, 11, 8, 2019-08-01
  [ CXC chemokine receptor 2,Lymphovascular niche,Myeloid-derived suppressor cells,Vascular endothelial growth factor-C ]

• A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway
  Journal of Experimental and Clinical Cancer Research, 38, 1, 2019-02-19
  [ C-met,Chemoresistance,ETS homologous factor,Keratin 16,miR-365-3p,Oral squamous cell carcinoma,β5-integrin ]

• Gjb4 serves as a novel biomarker for lung cancer and promotes metastasis and chemoresistance via Src activation
  Oncogene, 38, 6, 822-837, 2019-02-07

• Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application 06 Biological Sciences 0601 Biochemistry and Cell Biology 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
  Journal of Biomedical Science, 26, 1, 2019-01-14
  [ Chemoresistance,Connexins,GJIC,Metastasis,Therapeutics ]

• Identification of the novel role of CD24 as an oncogenesis regulator and therapeutic target for triple-negative breast cancer
  Molecular Cancer Therapeutics, 18, 1, 147-161, 2019-01-01

• Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the a-Ketoglutarate Signaling Pathway
  Cancer Research, 78, 11, 2799-2812, 2018-06-01

• EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis
  Oncogene, 36, 47, 6542-6554, 2017-11-23

• Low-dose glucocorticoids suppresses ovarian tumor growth and metastasis in an immunocompetent syngeneic mouse model
  PLoS ONE, 12, 6, 2017-06-01

• miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway
  Oncogenesis, 6, 5, 2017-05-01

• MMP-13 is involved in oral cancer cell metastasis
  Oncotarget, 7, 13, 17144-17161, 2016-03-29
  [ ECM,EMT,IF,MMP13,OSCC ]

• New dimension of glucocorticoids in cancer treatment
  Steroids, 111, 84-88, 2016-01-01
  [ Glucocorticoid receptor,Glucocorticoids,Inflammation,Metastasis,microRNA,Tumor ]

• Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy
  Clinical Cancer Research, 21, 18, 4073-4085, 2015-09-15

• Smoothed Lexis Diagrams With Applications to Lung and Breast Cancer Trends in Taiwan
  Journal of the American Statistical Association, 110, 511, 1000-1012, 2015-07-03
  [ Bayesian inference,Bernstein polynomial,Cancer surveillance,Female invasive breast cancer,Lung Cancer,Rate matrix ]

• Regulation of cancer metastasis by microRNAs
  Journal of Biomedical Science, 22, 1, 2015-01-16
  [ Breast cancer,EMT,Invasion,Metastasis,Migration,miRNAs ]

• Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B
  Nature Communications, 6, 2015-01-08

• VAV3 oncogene expression in colorectal cancer: Clinical aspects and functional characterization
  Scientific Reports, 5, 2015-01-01

• MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation
  Oncogene, 33, 43, 5109-5120, 2014-10-23

• MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis
  Oncogene, 33, 36, 4496-4507, 2014-09-04

• Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma
  International Journal of Cancer, 135, 4, 809-819, 2014-08-15
  [ BMP4,lung cancer,lung squamous cell carcinoma,SOX2 ]

• Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis
  Clinical Cancer Research, 20, 9, 2276-2288, 2014-05-01

• MiRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis
  Cancer Research, 74, 3, 751-764, 2014-02-01

• MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α
  International Journal of Cancer, 133, 4, 867-878, 2013-08-15
  [ HIF-1α,invasion/metastasis,microRNA,ovarian cancer,SOX4 ]

• Vav3-Rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence
  Cancer Research, 72, 12, 3000-3009, 2012-06-15

• Clinical significance of increased guanine nucleotide exchange factor Vav3 expression in human gastric cancer
  Molecular Cancer Research, 10, 6, 750-759, 2012-06-01

• Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity
  Oncotarget, 3, 11, 1401-1415, 2012-01-01
  [ Apoptosis,ERK,MCT-1,Ras,Shc,Tumor. ]

• Interferon-β signaling contributes to ras transformation
  PLoS ONE, 6, 8, 2011-08-29

• Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity
  Clinical Cancer Research, 16, 17, 4363-4373, 2010-09-01

• Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells
  Gynecologic Oncology, 114, 3, 516-522, 2009-09-01
  [ Carboplatin,Chemotherapy,Ovarian carcinoma,PI3 kinase,Rapamycin ]

• RACK1 and CIS mediate the degradation of BimEL in cancer cells
  Journal of Biological Chemistry, 283, 24, 16416-16426, 2008-06-13

• Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
  Journal of Biological Chemistry, 283, 21, 14665-14673, 2008-05-23

• Synergistic effect between EGF and TGF-β1 in inducing oncogenic properties of intestinal epithelial cells
  Oncogene, 27, 18, 2626-2634, 2008-04-17
  [ Colony formation,EGF,EMT,Invasion,TGF-β1 ]

• Regulation of cancer cell survival, migration, and invasion by twist: AKT2 comes to interplay
  Cancer Research, 68, 4, 957-960, 2008-02-15

• Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery
  Current Cancer Drug Targets, 8, 1, 2-6, 2008-02-01
  [ AKT,Anti-tumor target,Oncogene,Serine/threonine kinase,Signal transduction,Small molecule inhibitor ]