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王陸海

Wang, Lu-Hai

luhaiwang@mail.cmu.edu.tw

個人資料
著作概覽

期刊著作

Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients
Biomarker Research, 13, 1, 2025-12-01
[ Anti-HER2 therapy responder,Breast cancer,H-cell phenotype,Histamine N-methyltransferase,Nuclear translocation ]
CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model
Journal of Biomedical Science, 32, 1, 2025-12-01
[ CD24a,CD8+ T cells,CRISPR/Cas9 knockout,Macrophages,Triple-negative breast cancer,Tumor microenvironment ]
Development of a compound herbal formulation (HBK) with antitumor and antioxidant functions for cancer adjuvant therapy
Phytomedicine, 147, 2025-11-01
[ Botanical extract,Integrative medicine,Tumor microenvironment ]
ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis–Like Process That Directs Lung Tropism of Metastatic Breast Cancer
Cancer Research, 85, 7, 1199-1218, 2025-04-01
Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2
Nature Communications, 15, 1, 2024-12-01
Dissociation of the nuclear WWOX/TRAF2 switch renders UV/cold shock-mediated nuclear bubbling cell death at low temperatures
Cell Communication and Signaling, 22, 1, 2024-12-01
[ Cold shock,Molecular switch,Signaling,TRAF2,UV,WWOX ]
Investigation of the α9-nicotinic receptor single nucleotide polymorphisms induced oncogenic properties and molecular mechanisms in breast cancer
Human Molecular Genetics, 33, 22, 1948-1965, 2024-11-08
[ Breast cancer,Patient derived xenograft (PDX),Single-nucleotide polymorphisms (SNPs),Smoking exposure,α9-nicotinic acetylcholine receptor (α9-nAChR) ]
Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent relapse and metastasis of triple-negative breast cancer
Theranostics, 14, 5, 2167-2189, 2024-01-01
[ CXCL7/CXCR2,IL-6/IL-6R,Immunotherapy,MCT-1,PD-L1 ]
SCEL regulates switches between pro-survival and apoptosis of the TNF-α/TNFR1/NF-κB/c-FLIP axis to control lung colonization of triple negative breast cancer
Journal of Biomedical Science, 30, 1, 2023-12-01
[ Adalimumab,c-FLIP,Caspase 3,iTRAQ,mTNBC,NF-κB,SCEL,TNF-α,TNFR1 ]
Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment
Molecular Oncology, 17, 8, 1648-1665, 2023-08-01
[ 8-isopentenylnaringenin,EGFR TKI acquired resistance,lung adenocarcinoma,necrosis,synergistic effects ]
Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling
Journal of Biomedical Science, 29, 1, 2022-12-22
[ Cancer-associated fibroblast,Macrophages,Metastasis,NF-κB,Ovarian cancer,Periostin,TGF-β2 ]
MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway
Journal of Biomedical Science, 29, 1, 2022-12-01
[ Cancer stemness,Chemoresistance,Dasatinib,Integrin β4,Keratin 17,miR-485-5p,Oral squamous cell carcinoma,β-catenin ]
Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET
Oncogene, 41, 7, 997-1010, 2022-02-11
Nutrient supplements from selected botanicals mediated immune modulation of the tumor microenvironment and antitumor mechanism
Cancer Immunology, Immunotherapy, 70, 12, 3435-3449, 2021-12-01
[ Cancer immunotherapy,Immune modulating agents,MDSC,Nutrient supplement,TH1 ]
Monocytes secrete CXCL7 to promote breast cancer progression
Cell Death and Disease, 12, 12, 2021-12-01
LOC550643, a Long Non-coding RNA, Acts as Novel Oncogene in Regulating Breast Cancer Growth and Metastasis
Frontiers in Cell and Developmental Biology, 9, 2021-07-20
[ breast cancer,lncRNA,metastasis,microRNA,ncRNA ]
Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes
Theranostics, 11, 15, 7527-7545, 2021-01-01
[ Arginine starvation,cGAS-STING activation,DNA leakage,Epigenetic gene silencing ]
Effects of synthetic glucocorticoids on breast cancer progression
Steroids, 164, 2020-12-01
[ Breast cancer,Glucocorticoids,Metastasis,microRNA-708,Rap1B ]
DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits
Oncogene, 39, 37, 5933-5949, 2020-09-10
Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling
Scientific Reports, 9, 1, 2019-12-01
Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis
EMBO Reports, 20, 10, 2019-10-04
[ cystathionine gamma-lyase,hydrogen sulfide,IL-1beta,NF-kappaB,prostate cancer ]
Cancer-derived VEGF-C increases chemokine production in lymphatic endothelial cells to promote CXCR2-dependent cancer invasion and MDSC recruitment
Cancers, 11, 8, 2019-08-01
[ CXC chemokine receptor 2,Lymphovascular niche,Myeloid-derived suppressor cells,Vascular endothelial growth factor-C ]
A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway
Journal of Experimental and Clinical Cancer Research, 38, 1, 2019-02-19
[ C-met,Chemoresistance,ETS homologous factor,Keratin 16,miR-365-3p,Oral squamous cell carcinoma,β5-integrin ]
Gjb4 serves as a novel biomarker for lung cancer and promotes metastasis and chemoresistance via Src activation
Oncogene, 38, 6, 822-837, 2019-02-07
Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application 06 Biological Sciences 0601 Biochemistry and Cell Biology 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
Journal of Biomedical Science, 26, 1, 2019-01-14
[ Chemoresistance,Connexins,GJIC,Metastasis,Therapeutics ]
Identification of the novel role of CD24 as an oncogenesis regulator and therapeutic target for triple-negative breast cancer
Molecular Cancer Therapeutics, 18, 1, 147-161, 2019-01-01
Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the a-Ketoglutarate Signaling Pathway
Cancer Research, 78, 11, 2799-2812, 2018-06-01
EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis
Oncogene, 36, 47, 6542-6554, 2017-11-23
Low-dose glucocorticoids suppresses ovarian tumor growth and metastasis in an immunocompetent syngeneic mouse model
PLoS ONE, 12, 6, 2017-06-01
miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway
Oncogenesis, 6, 5, 2017-05-01
LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells
Oncogene, 35, 20, 2655-2663, 2016-05-19
MMP-13 is involved in oral cancer cell metastasis
Oncotarget, 7, 13, 17144-17161, 2016-03-29
[ ECM,EMT,IF,MMP13,OSCC ]
New dimension of glucocorticoids in cancer treatment
Steroids, 111, 84-88, 2016-01-01
[ Glucocorticoid receptor,Glucocorticoids,Inflammation,Metastasis,microRNA,Tumor ]
Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy
Clinical Cancer Research, 21, 18, 4073-4085, 2015-09-15
Smoothed Lexis Diagrams With Applications to Lung and Breast Cancer Trends in Taiwan
Journal of the American Statistical Association, 110, 511, 1000-1012, 2015-07-03
[ Bayesian inference,Bernstein polynomial,Cancer surveillance,Female invasive breast cancer,Lung Cancer,Rate matrix ]
Regulation of cancer metastasis by microRNAs
Journal of Biomedical Science, 22, 1, 2015-01-16
[ Breast cancer,EMT,Invasion,Metastasis,Migration,miRNAs ]
Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B
Nature Communications, 6, 2015-01-08
VAV3 oncogene expression in colorectal cancer: Clinical aspects and functional characterization
Scientific Reports, 5, 2015-01-01
MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation
Oncogene, 33, 43, 5109-5120, 2014-10-23
MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis
Oncogene, 33, 36, 4496-4507, 2014-09-04
Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma
International Journal of Cancer, 135, 4, 809-819, 2014-08-15
[ BMP4,lung cancer,lung squamous cell carcinoma,SOX2 ]
Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis
Clinical Cancer Research, 20, 9, 2276-2288, 2014-05-01
MiRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis
Cancer Research, 74, 3, 751-764, 2014-02-01
MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α
International Journal of Cancer, 133, 4, 867-878, 2013-08-15
[ HIF-1α,invasion/metastasis,microRNA,ovarian cancer,SOX4 ]
Vav3-Rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence
Cancer Research, 72, 12, 3000-3009, 2012-06-15
Clinical significance of increased guanine nucleotide exchange factor Vav3 expression in human gastric cancer
Molecular Cancer Research, 10, 6, 750-759, 2012-06-01
Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity
Oncotarget, 3, 11, 1401-1415, 2012-01-01
[ Apoptosis,ERK,MCT-1,Ras,Shc,Tumor. ]
Interferon-β signaling contributes to ras transformation
PLoS ONE, 6, 8, 2011-08-29
Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity
Clinical Cancer Research, 16, 17, 4363-4373, 2010-09-01
Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells
Gynecologic Oncology, 114, 3, 516-522, 2009-09-01
[ Carboplatin,Chemotherapy,Ovarian carcinoma,PI3 kinase,Rapamycin ]
RACK1 and CIS mediate the degradation of BimEL in cancer cells
Journal of Biological Chemistry, 283, 24, 16416-16426, 2008-06-13
Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
Journal of Biological Chemistry, 283, 21, 14665-14673, 2008-05-23
Synergistic effect between EGF and TGF-β1 in inducing oncogenic properties of intestinal epithelial cells
Oncogene, 27, 18, 2626-2634, 2008-04-17
[ Colony formation,EGF,EMT,Invasion,TGF-β1 ]
Regulation of cancer cell survival, migration, and invasion by twist: AKT2 comes to interplay
Cancer Research, 68, 4, 957-960, 2008-02-15
Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery
Current Cancer Drug Targets, 8, 1, 2-6, 2008-02-01
[ AKT,Anti-tumor target,Oncogene,Serine/threonine kinase,Signal transduction,Small molecule inhibitor ]

王陸海

Wang, Lu-Hai

現職

專長

專長簡述

最高學歷

相關連結

科技部學門領域

政府GRB研究專長領域

教育部學門領域

期刊著作

Development of a compound herbal formulation (HBK) with antitumor and antioxidant functions for cancer adjuvant therapy Phytomedicine, 147, 2025-11-01 [ Botanical extract,Integrative medicine,Tumor microenvironment ]

ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis–Like Process That Directs Lung Tropism of Metastatic Breast Cancer Cancer Research, 85, 7, 1199-1218, 2025-04-01

Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2 Nature Communications, 15, 1, 2024-12-01

Dissociation of the nuclear WWOX/TRAF2 switch renders UV/cold shock-mediated nuclear bubbling cell death at low temperatures Cell Communication and Signaling, 22, 1, 2024-12-01 [ Cold shock,Molecular switch,Signaling,TRAF2,UV,WWOX ]

Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent relapse and metastasis of triple-negative breast cancer Theranostics, 14, 5, 2167-2189, 2024-01-01 [ CXCL7/CXCR2,IL-6/IL-6R,Immunotherapy,MCT-1,PD-L1 ]

SCEL regulates switches between pro-survival and apoptosis of the TNF-α/TNFR1/NF-κB/c-FLIP axis to control lung colonization of triple negative breast cancer Journal of Biomedical Science, 30, 1, 2023-12-01 [ Adalimumab,c-FLIP,Caspase 3,iTRAQ,mTNBC,NF-κB,SCEL,TNF-α,TNFR1 ]

Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment Molecular Oncology, 17, 8, 1648-1665, 2023-08-01 [ 8-isopentenylnaringenin,EGFR TKI acquired resistance,lung adenocarcinoma,necrosis,synergistic effects ]

Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET Oncogene, 41, 7, 997-1010, 2022-02-11

Nutrient supplements from selected botanicals mediated immune modulation of the tumor microenvironment and antitumor mechanism Cancer Immunology, Immunotherapy, 70, 12, 3435-3449, 2021-12-01 [ Cancer immunotherapy,Immune modulating agents,MDSC,Nutrient supplement,TH1 ]

Monocytes secrete CXCL7 to promote breast cancer progression Cell Death and Disease, 12, 12, 2021-12-01

LOC550643, a Long Non-coding RNA, Acts as Novel Oncogene in Regulating Breast Cancer Growth and Metastasis Frontiers in Cell and Developmental Biology, 9, 2021-07-20 [ breast cancer,lncRNA,metastasis,microRNA,ncRNA ]

Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes Theranostics, 11, 15, 7527-7545, 2021-01-01 [ Arginine starvation,cGAS-STING activation,DNA leakage,Epigenetic gene silencing ]

Effects of synthetic glucocorticoids on breast cancer progression Steroids, 164, 2020-12-01 [ Breast cancer,Glucocorticoids,Metastasis,microRNA-708,Rap1B ]

DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits Oncogene, 39, 37, 5933-5949, 2020-09-10

Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling Scientific Reports, 9, 1, 2019-12-01

Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis EMBO Reports, 20, 10, 2019-10-04 [ cystathionine gamma-lyase,hydrogen sulfide,IL-1beta,NF-kappaB,prostate cancer ]

Cancer-derived VEGF-C increases chemokine production in lymphatic endothelial cells to promote CXCR2-dependent cancer invasion and MDSC recruitment Cancers, 11, 8, 2019-08-01 [ CXC chemokine receptor 2,Lymphovascular niche,Myeloid-derived suppressor cells,Vascular endothelial growth factor-C ]

Gjb4 serves as a novel biomarker for lung cancer and promotes metastasis and chemoresistance via Src activation Oncogene, 38, 6, 822-837, 2019-02-07

Identification of the novel role of CD24 as an oncogenesis regulator and therapeutic target for triple-negative breast cancer Molecular Cancer Therapeutics, 18, 1, 147-161, 2019-01-01

Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the a-Ketoglutarate Signaling Pathway Cancer Research, 78, 11, 2799-2812, 2018-06-01

EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis Oncogene, 36, 47, 6542-6554, 2017-11-23

Low-dose glucocorticoids suppresses ovarian tumor growth and metastasis in an immunocompetent syngeneic mouse model PLoS ONE, 12, 6, 2017-06-01

miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway Oncogenesis, 6, 5, 2017-05-01

LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells Oncogene, 35, 20, 2655-2663, 2016-05-19

MMP-13 is involved in oral cancer cell metastasis Oncotarget, 7, 13, 17144-17161, 2016-03-29 [ ECM,EMT,IF,MMP13,OSCC ]

New dimension of glucocorticoids in cancer treatment Steroids, 111, 84-88, 2016-01-01 [ Glucocorticoid receptor,Glucocorticoids,Inflammation,Metastasis,microRNA,Tumor ]

Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy Clinical Cancer Research, 21, 18, 4073-4085, 2015-09-15

Smoothed Lexis Diagrams With Applications to Lung and Breast Cancer Trends in Taiwan Journal of the American Statistical Association, 110, 511, 1000-1012, 2015-07-03 [ Bayesian inference,Bernstein polynomial,Cancer surveillance,Female invasive breast cancer,Lung Cancer,Rate matrix ]

Regulation of cancer metastasis by microRNAs Journal of Biomedical Science, 22, 1, 2015-01-16 [ Breast cancer,EMT,Invasion,Metastasis,Migration,miRNAs ]

Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B Nature Communications, 6, 2015-01-08

VAV3 oncogene expression in colorectal cancer: Clinical aspects and functional characterization Scientific Reports, 5, 2015-01-01

MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation Oncogene, 33, 43, 5109-5120, 2014-10-23

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis Oncogene, 33, 36, 4496-4507, 2014-09-04

Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma International Journal of Cancer, 135, 4, 809-819, 2014-08-15 [ BMP4,lung cancer,lung squamous cell carcinoma,SOX2 ]

Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis Clinical Cancer Research, 20, 9, 2276-2288, 2014-05-01

MiRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis Cancer Research, 74, 3, 751-764, 2014-02-01

MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α International Journal of Cancer, 133, 4, 867-878, 2013-08-15 [ HIF-1α,invasion/metastasis,microRNA,ovarian cancer,SOX4 ]

Vav3-Rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence Cancer Research, 72, 12, 3000-3009, 2012-06-15

Clinical significance of increased guanine nucleotide exchange factor Vav3 expression in human gastric cancer Molecular Cancer Research, 10, 6, 750-759, 2012-06-01

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity Oncotarget, 3, 11, 1401-1415, 2012-01-01 [ Apoptosis,ERK,MCT-1,Ras,Shc,Tumor. ]

Interferon-β signaling contributes to ras transformation PLoS ONE, 6, 8, 2011-08-29

Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity Clinical Cancer Research, 16, 17, 4363-4373, 2010-09-01

Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells Gynecologic Oncology, 114, 3, 516-522, 2009-09-01 [ Carboplatin,Chemotherapy,Ovarian carcinoma,PI3 kinase,Rapamycin ]

RACK1 and CIS mediate the degradation of BimEL in cancer cells Journal of Biological Chemistry, 283, 24, 16416-16426, 2008-06-13

Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function Journal of Biological Chemistry, 283, 21, 14665-14673, 2008-05-23

Synergistic effect between EGF and TGF-β1 in inducing oncogenic properties of intestinal epithelial cells Oncogene, 27, 18, 2626-2634, 2008-04-17 [ Colony formation,EGF,EMT,Invasion,TGF-β1 ]

Regulation of cancer cell survival, migration, and invasion by twist: AKT2 comes to interplay Cancer Research, 68, 4, 957-960, 2008-02-15

Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery Current Cancer Drug Targets, 8, 1, 2-6, 2008-02-01 [ AKT,Anti-tumor target,Oncogene,Serine/threonine kinase,Signal transduction,Small molecule inhibitor ]

Development of a compound herbal formulation (HBK) with antitumor and antioxidant functions for cancer adjuvant therapy
Phytomedicine, 147, 2025-11-01
[ Botanical extract,Integrative medicine,Tumor microenvironment ]

ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis–Like Process That Directs Lung Tropism of Metastatic Breast Cancer
Cancer Research, 85, 7, 1199-1218, 2025-04-01

Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2
Nature Communications, 15, 1, 2024-12-01

Dissociation of the nuclear WWOX/TRAF2 switch renders UV/cold shock-mediated nuclear bubbling cell death at low temperatures
Cell Communication and Signaling, 22, 1, 2024-12-01
[ Cold shock,Molecular switch,Signaling,TRAF2,UV,WWOX ]

Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent relapse and metastasis of triple-negative breast cancer
Theranostics, 14, 5, 2167-2189, 2024-01-01
[ CXCL7/CXCR2,IL-6/IL-6R,Immunotherapy,MCT-1,PD-L1 ]

SCEL regulates switches between pro-survival and apoptosis of the TNF-α/TNFR1/NF-κB/c-FLIP axis to control lung colonization of triple negative breast cancer
Journal of Biomedical Science, 30, 1, 2023-12-01
[ Adalimumab,c-FLIP,Caspase 3,iTRAQ,mTNBC,NF-κB,SCEL,TNF-α,TNFR1 ]

Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment
Molecular Oncology, 17, 8, 1648-1665, 2023-08-01
[ 8-isopentenylnaringenin,EGFR TKI acquired resistance,lung adenocarcinoma,necrosis,synergistic effects ]

Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET
Oncogene, 41, 7, 997-1010, 2022-02-11

Nutrient supplements from selected botanicals mediated immune modulation of the tumor microenvironment and antitumor mechanism
Cancer Immunology, Immunotherapy, 70, 12, 3435-3449, 2021-12-01
[ Cancer immunotherapy,Immune modulating agents,MDSC,Nutrient supplement,TH1 ]

Monocytes secrete CXCL7 to promote breast cancer progression
Cell Death and Disease, 12, 12, 2021-12-01

LOC550643, a Long Non-coding RNA, Acts as Novel Oncogene in Regulating Breast Cancer Growth and Metastasis
Frontiers in Cell and Developmental Biology, 9, 2021-07-20
[ breast cancer,lncRNA,metastasis,microRNA,ncRNA ]

Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes
Theranostics, 11, 15, 7527-7545, 2021-01-01
[ Arginine starvation,cGAS-STING activation,DNA leakage,Epigenetic gene silencing ]

Effects of synthetic glucocorticoids on breast cancer progression
Steroids, 164, 2020-12-01
[ Breast cancer,Glucocorticoids,Metastasis,microRNA-708,Rap1B ]

DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits
Oncogene, 39, 37, 5933-5949, 2020-09-10

Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling
Scientific Reports, 9, 1, 2019-12-01

Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis
EMBO Reports, 20, 10, 2019-10-04
[ cystathionine gamma-lyase,hydrogen sulfide,IL-1beta,NF-kappaB,prostate cancer ]

Cancer-derived VEGF-C increases chemokine production in lymphatic endothelial cells to promote CXCR2-dependent cancer invasion and MDSC recruitment
Cancers, 11, 8, 2019-08-01
[ CXC chemokine receptor 2,Lymphovascular niche,Myeloid-derived suppressor cells,Vascular endothelial growth factor-C ]

Gjb4 serves as a novel biomarker for lung cancer and promotes metastasis and chemoresistance via Src activation
Oncogene, 38, 6, 822-837, 2019-02-07

Identification of the novel role of CD24 as an oncogenesis regulator and therapeutic target for triple-negative breast cancer
Molecular Cancer Therapeutics, 18, 1, 147-161, 2019-01-01

Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the a-Ketoglutarate Signaling Pathway
Cancer Research, 78, 11, 2799-2812, 2018-06-01

EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis
Oncogene, 36, 47, 6542-6554, 2017-11-23

Low-dose glucocorticoids suppresses ovarian tumor growth and metastasis in an immunocompetent syngeneic mouse model
PLoS ONE, 12, 6, 2017-06-01

miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway
Oncogenesis, 6, 5, 2017-05-01

LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells
Oncogene, 35, 20, 2655-2663, 2016-05-19

MMP-13 is involved in oral cancer cell metastasis
Oncotarget, 7, 13, 17144-17161, 2016-03-29
[ ECM,EMT,IF,MMP13,OSCC ]

New dimension of glucocorticoids in cancer treatment
Steroids, 111, 84-88, 2016-01-01
[ Glucocorticoid receptor,Glucocorticoids,Inflammation,Metastasis,microRNA,Tumor ]

Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy
Clinical Cancer Research, 21, 18, 4073-4085, 2015-09-15

Smoothed Lexis Diagrams With Applications to Lung and Breast Cancer Trends in Taiwan
Journal of the American Statistical Association, 110, 511, 1000-1012, 2015-07-03
[ Bayesian inference,Bernstein polynomial,Cancer surveillance,Female invasive breast cancer,Lung Cancer,Rate matrix ]

Regulation of cancer metastasis by microRNAs
Journal of Biomedical Science, 22, 1, 2015-01-16
[ Breast cancer,EMT,Invasion,Metastasis,Migration,miRNAs ]

Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B
Nature Communications, 6, 2015-01-08

VAV3 oncogene expression in colorectal cancer: Clinical aspects and functional characterization
Scientific Reports, 5, 2015-01-01

MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation
Oncogene, 33, 43, 5109-5120, 2014-10-23

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis
Oncogene, 33, 36, 4496-4507, 2014-09-04

Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma
International Journal of Cancer, 135, 4, 809-819, 2014-08-15
[ BMP4,lung cancer,lung squamous cell carcinoma,SOX2 ]

Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis
Clinical Cancer Research, 20, 9, 2276-2288, 2014-05-01

MiRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis
Cancer Research, 74, 3, 751-764, 2014-02-01

MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α
International Journal of Cancer, 133, 4, 867-878, 2013-08-15
[ HIF-1α,invasion/metastasis,microRNA,ovarian cancer,SOX4 ]

Vav3-Rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence
Cancer Research, 72, 12, 3000-3009, 2012-06-15

Clinical significance of increased guanine nucleotide exchange factor Vav3 expression in human gastric cancer
Molecular Cancer Research, 10, 6, 750-759, 2012-06-01

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity
Oncotarget, 3, 11, 1401-1415, 2012-01-01
[ Apoptosis,ERK,MCT-1,Ras,Shc,Tumor. ]

Interferon-β signaling contributes to ras transformation
PLoS ONE, 6, 8, 2011-08-29

Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity
Clinical Cancer Research, 16, 17, 4363-4373, 2010-09-01

Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells
Gynecologic Oncology, 114, 3, 516-522, 2009-09-01
[ Carboplatin,Chemotherapy,Ovarian carcinoma,PI3 kinase,Rapamycin ]

RACK1 and CIS mediate the degradation of BimEL in cancer cells
Journal of Biological Chemistry, 283, 24, 16416-16426, 2008-06-13

Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
Journal of Biological Chemistry, 283, 21, 14665-14673, 2008-05-23

Synergistic effect between EGF and TGF-β1 in inducing oncogenic properties of intestinal epithelial cells
Oncogene, 27, 18, 2626-2634, 2008-04-17
[ Colony formation,EGF,EMT,Invasion,TGF-β1 ]

Regulation of cancer cell survival, migration, and invasion by twist: AKT2 comes to interplay
Cancer Research, 68, 4, 957-960, 2008-02-15

Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery
Current Cancer Drug Targets, 8, 1, 2-6, 2008-02-01
[ AKT,Anti-tumor target,Oncogene,Serine/threonine kinase,Signal transduction,Small molecule inhibitor ]