國立中央大學教師履歷平台

期刊著作

• O-GlcNAcylation expression predicts a favorable prognosis and mitigates malignant phenotypes via MYCN suppression in neuroblastoma
  Molecular and Cellular Pediatrics, 13, 1, 2026-12-01
  [ GSK3β,MYCN,Neuroblastoma,O-GlcNAc ]

• Elucidating Causal Associations Between Immune Cells, Circulating Inflammatory Proteins, and Chronic Inflammatory Demyelinating Polyneuropathy: A Two-Sample Two-Step Mendelian Randomization Study
  Journal of the Peripheral Nervous System, 31, 1, 2026-03-01
  [ chronic inflammatory demyelinating polyneuropathy,circulating inflammatory proteins,immune cells,Mendelian randomization ]

• Targeting neuroblastoma with 3β,5α-tetrahydrocorticosterone: Activation of aryl hydrocarbon receptor inhibits tumor growth, metastasis, and stemness while promoting neural differentiation
  Chemico-Biological Interactions, 421, 2025-11-01
  [ 3β,5α-tetrahydrocorticosterone,AHR,Differentiation,Metastasis,Neuroblastoma,Stemness ]

• Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH-MYCN transgenic mice
  Bioengineering and Translational Medicine, 10, 4, 2025-07-01
  [ BioNDP,chemotherapy,drug screening,neuroblastoma,synergy,TH-MYCN mice ]

• Enhancing cisplatin efficacy in hepatocellular carcinoma with selenocystine: The suppression of DNA repair and inhibition of proliferation in hepatoma cells
  Chemico-Biological Interactions, 405, 2025-01-05
  [ Cisplatin,DNA damage,DNA repair activity,Hepatocellular carcinoma,Selenocystine ]

• High-yield BMP2 expression in rice cells via CRISPR and endogenous αAmy3 promoter
  Applied Microbiology and Biotechnology, 108, 1, 2024-12-01
  [ CRISPR/Cas 9 knock-in,Human BMP2 recombinant protein,Rice suspension cells,Sugar,αAmy3 promoter ]

• Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells
  Chemico-Biological Interactions, 365, 2022-09-25
  [ Apoptosis,DDR,Homologous recombination repair,ROS,Selenocysteine ]

• Calreticulin Regulates β1-Integrin mRNA Stability in PC-3 Prostate Cancer Cells
  Biomedicines, 10, 3, 2022-03-01

• Phosphatidylinositol-4-phosphate 5-kinase type 1α attenuates Aβ production by promoting non-amyloidogenic processing of amyloid precursor protein
  FASEB Journal, 34, 9, 12127-12146, 2020-09-01
  [ Alzheimer's disease,amyloid precursor protein,amyloid-β,phosphatidylinositol-4-phosphate 5-kinase type 1 α ]

• Activation of aryl hydrocarbon receptor by kynurenine impairs progression and metastasis of neuroblastoma
  Cancer Research, 79, 21, 5550-5562, 2019-11-01

• Novel Endogenous Ligands of Aryl Hydrocarbon Receptor Mediate Neural Development and Differentiation of Neuroblastoma
  ACS Chemical Neuroscience, 10, 9, 4031-4042, 2019-09-18
  [ 3α,5α-Tetrahydrocorticosterone,3α,5β-Tetrahydrocorticosterone,Aryl Hydrocarbon Receptor (AHR),Myelination,Neural development,Neuroblastoma ]

• Mechanisms of lysophosphatidic acid-mediated lymphangiogenesis in prostate cancer
  Cancers, 10, 11, 2018-11-01
  [ LPA,LPA receptor,Lymphangiogenesis,Prostate cancer,VEGF-C ]

• Quantitative measurement of γ-secretase-mediated amyloid precursor protein and notch cleavage in cell-based luciferase reporter assay platforms
  Journal of Visualized Experiments, 2018, 131, 2018-01-25
  [ Alzheimer’s disease,Amyloid precursor protein,Amyloid-β,ErbB2,Firefly luciferase,Issue 131,Neuroscience,Notch,γ-secretase ]

• VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma
  Scientific Reports, 7, 1, 2017-12-01

• ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer’s disease
  Proceedings of the National Academy of Sciences of the United States of America, 114, 15, E3129-E3138, 2017-04-11
  [ Alzheimer’s disease,Autophagy,Aβ,C99,ErbB2 ]

• Observation of "wired" cell communication over 10- μ m and 20- μ m poly(dimethylsiloxane) barriers in tetracycline inducible expression systems
  Journal of Applied Physics, 119, 2, 2016-01-14

• Calreticulin Regulates VEGF-A in Neuroblastoma Cells
  Molecular Neurobiology, 52, 1, 758-770, 2015-08-25
  [ Calreticulin,Neuroblastoma,Neuronal differentiation,VEGF ]

• MDA5 complements TLR3 in suppression of neuroblastoma
  Oncotarget, 6, 28, 24935-24946, 2015-01-01
  [ MDA5,Neuroblastoma,Poly(I:C),RIG-I,TLR3 ]

• Experimental demonstration of bindingless signal delivery in human cells via microfluidics
  Journal of Applied Physics, 116, 4, 2014-07-28

• Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells
  Biochemical Journal, 460, 1, 69-78, 2014-05-15
  [ Activation,Adhesion calreticulin,Fucosylation,Fucosyltransferase 1 (FUT1),Integrin,RNA stability ]

• Aryl hydrocarbon receptor downregulates MYCN expression and promotes cell differentiation of neuroblastoma
  PLoS ONE, 9, 2, 2014-02-21

• Toll-like receptor 3 expression inhibits cell invasion and migration and predicts a favorable prognosis in neuroblastoma
  Cancer Letters, 336, 2, 338-346, 2013-08-19
  [ Migration,Neuroblastoma,Poly(I:C),Prognosis,Toll-like receptor 3 ]

• Aromatic hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factor-A expression in PC-3 prostate cancer cells
  Biochemical and Biophysical Research Communications, 437, 3, 440-445, 2013-08-02
  [ AHR,HIF-1,LPA,VEGF ]

• Establishment of a cell-free bioassay for detecting dioxin-like compounds
  Toxicology Mechanisms and Methods, 23, 6, 464-470, 2013-07-01
  [ AhR,Arnt,Bioassay,Dioxin ]

• Characterization of neuroblastic tumors using 18F-FDOPA PET
  Journal of Nuclear Medicine, 54, 1, 42-49, 2013-01-01
  [ 18F-FDOPA,Ganglioneuroma,Neuroblastoma,Positron emission tomography,Sensitivity and specificity ]

• Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR
  FEBS Letters, 585, 22, 3582-3586, 2011-11-16
  [ AHR,Cell differentiation,MicroRNA,miR-124,Neuroblastoma ]

研討會著作

• EZH2 inhibition de-represses AHR expression and enhances its ligand-activated signaling in neuroblastoma therapy.
  2025-05-25
  [ Neuroblastoma, EZH2, AHR ]

• Develop the novel tetrahydrocorticosterol therapy in neuroblastoma.
  2023-12-02
  [ Neuroblastoma,AHR,tetrahydrocorticosterone ]

• The therapeutic potential of tetrahydrocorticosterone in neuroblastoma
  2023-07-02
  [ neuroblastoma,tetrahydrocorticosterone,AHR ]

• Identification of TIMP-3 as a metastatic regulator of neuroblastoma.
  2023-05-14
  [ Neuroblastoma, TIMP3, metastasis, ERBB1, ERBB2 ]