國立中央大學教師履歷平台

期刊著作

• Development of attenuated Orf virus as a safe oncolytic viral vector for nasopharyngeal carcinoma treatment
  Virology Journal, 22, 1, 2025-12-01
  [ Cell death,Nasopharyngeal carcinoma,NK cells,Oncolytic-attenuated ORFV,Xenograft model ]

• Tumor cell-derived ISG15 promotes fibroblast recruitment in oral squamous cell carcinoma via CD11a-dependent glycolytic reprogramming
  Oncogenesis, 14, 1, 2025-12-01

• Photoactive nanocatalysts as DTT-assisted BSA-AuNCs with enhanced oxidase-mimicking ability for sensitive fluorometric detection of antioxidants
  Journal of Nanobiotechnology, 22, 1, 2024-12-01
  [ Antioxidants,DTT@BSA-AuNCs,Fluorescence,Oxidase-like nanozymes,Photocatalysis ]

• A 3-gene signature comprising CDH4, STAT4 and EBV-encoded LMP1 for early diagnosis and predicting disease progression of nasopharyngeal carcinoma
  Discover Oncology, 14, 1, 2023-12-01
  [ CDH4,CYLD,EBV-encoded LMP1,Nasopharyngeal carcinoma,STAT4 ]

• Epstein-Barr viral product-containing exosomes promote fibrosis and nasopharyngeal carcinoma progression through activation of YAP1/FAPα signaling in fibroblasts
  Journal of Experimental and Clinical Cancer Research, 41, 1, 2022-08-20
  [ EBV,Epstein-Barr virus,Exosome,FAPα,Fibroblast,Fibroblast activation protein alpha,Fibrosis,Nasopharyngeal carcinoma,NPC,YAP1 ]

• Characterization of recurrent relevant genes reveals a novel role of rpl36a in radioresistant oral squamous cell carcinoma
  Cancers, 13, 22, 2021-11-01
  [ Oral cancer,Oral cavity squamous cell carcinoma,OSCC,Radioresistance,Radiotherapy,RPL36A ]

• Epstein-barr virus induces adipocyte dedifferentiation to modulate the tumor microenvironment
  Cancer Research, 81, 12, 3283-3294, 2021-06-01

• miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma
  Neoplasia, 22, 12, 789-799, 2020-12-01
  [ BRAF inhibitor,Melanoma,miR-524-5p,miRNA,Resistance ]

• WNK1 kinase stimulates angiogenesis to promote tumor growth and metastasis
  Cancers, 12, 3, 2020-03-01
  [ Colorectal cancer , Hepatocellular carcinoma , Tumor-induced angiogenesis , With-no-lysine (K) kinase I , Zebrafish ]

• Association of subcutaneous and visceral adipose tissue with overall survival in Taiwanese patients with bone metastases – results from a retrospective analysis of consecutively collected data
  PLoS ONE, 15, 1, 2020-01-01

• Prognostic significance of pretreatment neutrophil-to-lymphocyte ratio in older patients with metastatic cancer
  Journal of Geriatric Oncology, 10, 5, 757-762, 2019-09-01

• Tail shape evolution dynamics of MDCK cells on fibronectin substrates
  Biomedical Physics and Engineering Express, 5, 4, 2019-05-16
  [ actin filament , cell migration , cell shape evolution , focal adhesion , tail retraction , treadmilling motion ]

• Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling
  Nature Communications, 9, 1, 2018-12-01

• Enhancing Cancer Cell Collective Motion and Speeding up Confluent Endothelial Dynamics through Cancer Cell Invasion and Aggregation
  Physical Review Letters, 121, 1, 2018-07-03

• EBV oncogene N-LMP1 induces CD4 T cell-mediated angiogenic blockade in the murine tumor model
  Journal of Immunology, 194, 9, 4577-4587, 2015-01-01

• Role of leukemia inhibitory factor in nasopharyngeal carcinogenesis
  Molecular and Cellular Oncology, 1, 1, 2014-01-01
  [ Epstein-Barr virus , leukemia inhibitory factor , mTOR , nasopharyngeal carcinoma , p70S6K , radioresistance ]

• Secretome profiling of primary cells reveals that THBS2 is a salivary biomarker of oral cavity squamous cell carcinoma
  Journal of Proteome Research, 13, 11, 4796-4807, 2014-01-01
  [ biomarker , oral cavity squamous cell carcinoma , primary cell , saliva , secretome , thrombospondin-2 ]

• Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance
  Journal of Clinical Investigation, 123, 12, 5269-5283, 2013-12-02

• Epstein-barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells
  PLoS Pathogens, 8, 5, 2012-05-01

• Quantitative plasma proteome analysis reveals aberrant level of blood coagulation-related proteins in nasopharyngeal carcinoma
  Journal of Proteomics, 74, 5, 744-757, 2011-05-01
  [ Blood coagulation , Nasopharyngeal carcinoma , Plasma kallikrein , Plasma proteome , Protein fractionation , Tumor marker ]

• Neural stem cells secrete factors that promote auditory cell proliferation via a leukemia inhibitory factor signaling pathway
  , 88, 15, 3308-3318, 2010-11-15
  [ Cell culture , Cell proliferation , Cochlea , Cytokines , Leukemia inhibitory factor , Neural stem cell ]

• Gα12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization
  Cancer Research, 69, 15, 6122-6130, 2009-08-01

• Temporal transcription program of recombinant Autographa californica multiple nucleopolyhedrosis virus
  Journal of Virology, 80, 18, 8989-8999, 2006-09-01

• A bayes regression approach to array-CGH data
  Statistical Applications in Genetics and Molecular Biology, 5, 1, 2006-01-01
  [ Change point problem , Comparative genomic hybridization , DNA copy number imbalance ]

研討會著作

• Bimetallic photonanozyme catalysts for fluorometric analysis of total antioxidant capacity in human saliva
  2025-01-01
  [ Bimetallic nanocluster,Fluorescence assay,Oxidative stress,Photonanozyme,Reactive oxygen species,Total antioxidative capacity ]

• Deciphering the Systemic Immune Responses Mediated by Radiotherapy in Stage I NPC Patients
  2024-08-03
  [ radiotherapy,immune,nasopharyngeal carcinoma ]

• Radiotherapy-mediated immune modulatory responses in patients with stage I nasopharyngeal carcinoma
  2024-05-04
  [ immune response,nasopharyngeal carcinoma ]

• Leukemia Inhibitory Factor Modulates Macrophage Immune Response Through YAP1 signaling in Oral Squamous Cell Carcinoma.
  2023-05-06
  [ LIF, leukemia inhibitory factor, macrophage, oral cancer ]

• The multifaceted roles of leukemia inhibitor factor in tuning the immune microenvironment of oral squamous cell carcinoma
  200, 2023-05-06
  [ 頭頸癌，免疫治療，白血病抑制因子，單細胞定序，腫瘤微環境，免疫檢查點 ]

• EBV positive NPC-derived exosomes promote macrophage M2 polarization via activating MST1R signaling
  200, 2023-05-06
  [ Epstein-Barr virus, EBV, nasopharyngeal carcinoma, NPC, exosome ]

• Leukemia inhibitory factor regulates macrophage immune response in head and neck squamous cell carcinoma
  2023-04-14
  [ LIF, leukemia inhibitory factor, macrophage, oral cancer ]

• EBV positive NPC-derived exosomes promote macrophage M2 polarization via activating MST1R and YAP1 signalings
  2023-04-14
  [ Epstein-Barr virus, EBV, nasopharyngeal carcinoma, exosome, macrophage ]

• NPC-Derived Exosomal LMP1 Promotes Macrophage M2 Polarization Via Activating MST1R Signaling
  2023-03-18
  [ Epstein-Barr virus, latent membrane protein 1, exosome ]

• Systemic Immune Signatures Associated with Radiation Therapy in Nasopharyngeal Carcinoma at Single-Cell Resolution.
  2022-12-10
  [ radiotherapy, radiation, single-cell, radioresistance ]

• Leukemia Inhibitor Factor Promotes Polarization and Immune Regulations of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma
  2022-04-30
  [ leukemia inhibitory factor, oral cancer, tumor microenvironment, macrophage ]

• Investigating the Role of NPC-Derived Exosomes in Regulating Macrophage Immunity
  2022-04-30
  [ exosome, macrophage, immune, nasopharyngeal carcinoma ]

• Decoding the Systemic Immune Signatures Associated with Radiation Therapy in Nasopharyngeal Carcinoma
  2022-04-30
  [ radiation, radiotherapy, single cell sequencing, nasopharyngeal carcinoma ]

• EBV-products containing exosomes remodel NPC tumor microenvironment by activating fibroblasts
  Cancer Res 2022;82(12_Suppl):Abstract nr 3192., 2022-04-08
  [ fibroblast, exosome, nasopharygeal carcinoma ]

• Nasopharyngeal Carcinoma-Derived EBV Products-Containing Exosomes Regulate Macrophage Polarization and Immune Responses
  2022-03-26
  [ nasopharyngeal carcinoma, immune, macrophage ]

• Investigating the NPC-derived Exosomes-Mediated Effects on Macrophage Polarization and Immune Response
  2021-09-04
  [ macrophage, immune response, NPC, RNA sequencing ]

• EBV Product-Containing Exosomes Remodel the Tumor Microenvironment by Activating Stromal Fibroblasts
  2021-09-04
  [ exosome, fibroblast, EBV, NPC ]

• Emerging role of exosomes in cancer: clinical insights and diagnostic potential
  2021-06-05
  [ exosome, cancer ]

• Interactions between Epstein-Barr virus and tumor-associated adipocytes
  2020-03-02
  [ EBV, adipocyte, tumor microenvironment, lipid ]

• Epstein-Barr virus dedifferentiates adipocytes and modulates tumor microenvironment
  2019-05-04
  [ EBV, fibroblast, adipocyte differentiation ]

• The Molecular basis of LIF-mediated NPC metastasis
  79, 2019-03-29
  [ nasopharyngeal caricinoma, LIF, YAP1, focal adhesion ]

• SRC-YAP1 Signaling Modulates Activation of Fibroblasts in the NPC Tumor Microenvironment
  2018-06-10
  [ YAP1, NPC, SRC ]