教師個人簡歷
現職
國立中央大學
生醫理工學院生命科學系
副教授
專長
基因組學(NGS數據分析)
分子生物學
發育遺傳
專長簡述
基因組學(NGS數據分析)、分子生物學、發育遺傳
最高學歷
美國New York University
生物學類
博士
政府GRB研究專長領域
教育部學門領域
其他補助
-
應用AI翻轉教室強化生物化學實驗課程成效的行動方案
1130801~1140731
[AI翻轉教室 , Applying AI to Flip the Classroom]
高教深耕計畫
-
113年度教學實踐研究推動與分析計畫-粘仲毅老師
1130101~1131231
-
以教育大數據為基之精準教育(5)
1120601~1121231
國科會計畫統計
-
應用STARR-Seq技術研究由先驅因子Zelda介導的基因組重編程機制
1140801~1150731
-
利用STARR-SEQ與體學統合分析高通量鑒定果蠅早期胚胎發育強化子之功能與活性
1100801~1110731
[胚胎發育,表觀遺傳,合子基因體啟動,基因調控,母代合子過渡,核小體佔據,基因網,調控組 , embryogenesis,zygotic genome activation,gene regulation,maternal-to-zygotic transition,nucleosome occupancy,Zelda,enhancer,regulatory genome,gene network] -
利用STARR-SEQ與體學統合分析高通量鑒定果蠅早期胚胎發育強化子之功能與活性
1090801~1100731
[胚胎發育,表觀遺傳,合子基因體啟動,基因調控,母代合子過渡,核小體佔據,基因網,調控組 , embryogenesis,zygotic genome activation,gene regulation,maternal-to-zygotic transition,nucleosome occupancy,Zelda,enhancer,regulatory genome,gene network] -
利用體學研究方法分析果蠅之調控組
1080801~1090731
[調控組 果蠅胚胎發育 , regulatome, transcriptome, Maternal-to-Zygotic transition, Zelda, STARR-Seq, enhancer, embryogenesis] -
果蠅合子基因組啟動與胚胎多潛能分子機制之探討
1070801~1080731
[胚胎發育,表觀遺傳,合子基因體啟動,基因調控,母代合子過渡,核小體佔據,胚胎多能分化性, , embryogenesis, zygotic genome activation, gene regulation, epigenetic, maternal-to-zygotic transition, nucleosome occupancy, embryonic pluripotency, Zelda, ehancer]
期刊著作
-
Microplastic and nanoplastic exposure and risk of diabetes mellitus
World Journal of Clinical Cases, 13, 3, 98110, 2025-01-26
[ Microplastics; Nanoplastics; Plastic pollution, Diabetes mellitus; Insulin resistance ] -
Multi-level regulation of even-skipped stripes by the ubiquitous factor Zelda
Development (Cambridge), 150, 23, 2023-12-01
[ Drosophila,Cis regulation,Cross-repression,Embryogenesis,Even-skipped,Transcriptional regulation,Zelda ] -
MicroRNA-152-3p and MicroRNA-196a-5p Are Downregulated When Müller Cells Are Promoted by Components of the Internal Limiting Membrane: Implications for Macular Hole Healing
International Journal of Molecular Sciences, 24, 24, 2023-12-01
[ internal limiting membrane,macular hole,microRNA,miR-152-3p,miR-196a-5p,Müller cells ] -
Delivery and Transcriptome Assessment of an In Vitro Three-Dimensional Proximal Tubule Model Established by Human Kidney 2 Cells in Clinical Gelatin Sponges
International Journal of Molecular Sciences, 24, 21, 2023-11-01
[ comparative transcriptome analysis,gelatin spongy scaffold,HK-2 cells,nephrotoxicity,proximal tubule cells,three-dimensional culture,two-dimensional culture ] -
Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis
Cell Death and Disease, 13, 12, 2022-12-01 -
Calcitriol and enamel matrix derivative differentially regulated cemento-induction and mineralization in human periodontal ligament-derived cells
Journal of Periodontology, 93, 10, 1553-1565, 2022-10-01
[ cementum,gene expression,periodontal regeneration ] -
Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells
Chemico-Biological Interactions, 365, 2022-09-25
[ Apoptosis,DDR,Homologous recombination repair,ROS,Selenocysteine ] -
Recurrence Rate of Proximal Contact Loss Between Implant Restorations and Adjacent Teeth After Proximal Contact Repair: A Retrospective Study
International Journal of Oral and Maxillofacial Implants, 37, 3, 579-585, 2022-01-01
[ Implant complication,Implant prosthesis,Proximal contact loss,Recurrence rate,Risk factors ] -
Di(2-ethylhexyl)phthalate exposure exacerbates metabolic disorders in diet-induced obese mice
Food and Chemical Toxicology, 156, 2021-10-01
[ Glucose intolerance,Hepatic steatosis,Insulin resistance,Macrophage infiltration,Obesity,Steatohepatitis ] -
Application Of Dental Stem Cells In Three-Dimensional Tissue Regeneration
World Journal of Stem Cells, 13, 11, 1610-1624, 2021-01-01
[ Dental,Dental pulp stem cells,Dental stem cells,Periodontal ligament stem cells,Stem cells from apical papilla,Stem cells from human exfoliated deciduous teeth ] -
Phthalate exposure causes browning-like effects on adipocytes in vitro and in vivo
Food and Chemical Toxicology, 142, 2020-08-01
[ Energy metabolism , Fat cells , Fatty acid oxidation , Mitochondria , Peroxisomes , Plasticizer ] -
4-Aminobiphenyl inhibits the DNA homologous recombination repair in human liver cells: The role of miR-630 in downregulating RAD18 and MCM8
Toxicology, 440, 2020-07-01 -
The prevalence and associated factors of proximal contact loss between implant restoration and adjacent tooth after function: A retrospective study
Clinical Implant Dentistry and Related Research, 22, 3, 351-358, 2020-06-01 -
Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation
Genome Research, 25, 11, 1703-1714, 2015-11-01 -
Zelda potentiates morphogen activity by increasing chromatin accessibility
Current Biology, 24, 12, 1341-1346, 2014-06-16 -
Co-activation of microRNAs by Zelda is essential for early drosophila development
Development (Cambridge), 141, 10, 2108-2118, 2014-01-01
[ Co-activation , Gene network , MicroRNA , MZT , Zelda ] -
Microarray-based capture of novel expressed cell type-specific transfrags (CoNECT) to annotate tissue-specific transcription in drosophila melanogaster
G3: Genes, Genomes, Genetics, 2, 8, 873-882, 2012-08-01
[ Array capture , Enrichment , Transcript isoforms , Transcriptome ] -
Temporal coordination of gene networks by Zelda in the early Drosophila embryo
PLoS Genetics, 7, 10, 2011-10-01 -
The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila
Nature, 456, 7220, 400-403, 2008-11-20 -
Increase of lipid peroxidation by cisplatin in WI38 cells but not in SV40-transformed WI38 cells
Journal of Biochemical and Molecular Toxicology, 17, 1, 39-46, 2003-04-16
[ 4-Hydroxy-2-nonenal,Cisplatin,F2-isoprostanes,Lipid peroxidation,Mitochondrial gene expression,Transformed cells ]
研討會著作
-
Blockage of Nrf2 and Autophagy by L-selenocystine Induces Selective Death in Nrf2-addicted Colorectal Cancer Cells through p62-Keap-1-Nrf2 Axis
2023-07-17
[ Colorectal Cancer,Autophagy,Nrf2 addiction,ROS,SeC ]
校內獲獎
- 114 研究傑出獎
- 113 優良論文貢獻獎
- 106 新進教師補助
- 105 新聘傑出獎(舊制)
國立中央大學