國立中央大學
教師個人簡歷
現職
國立中央大學
生醫理工學院生醫科學與工程學系
副教授
國立中央大學
國際交流暨招生組
組長
專長
生物資訊學
資料探勘
蛋白質體學
代謝體學
Bioinformatics
data mining
proteomics
metabolomics
專長簡述
生物資訊學、資料探勘、蛋白質體學、 代謝體學
最高學歷
國立陽明大學
生物醫學資訊研究所
博士
政府GRB研究專長領域
教育部學門領域
高教深耕計畫
-
應用人工智慧於胰臟癌跨組學數據的深度解碼
1140101~1141231
[胰管腺癌,蛋白質體學,影像組學,機器學習,人工智慧 , pancreatic ductal adenocarcinoma cancer,proteomics,radiomics,machine learning,artificial intelligence] -
應用精準醫療模式於類風濕疾病成因探討、共病關係與用藥關係
1130101~1131231
[類風溼性關節炎,精準醫療,機器學習,蛋白質體學 , rheumatoid arthritis,precision medicine,machine learning,proteomics] -
新進/年輕教師學術研究補助-張彙音
1110101~1111231
國科會計畫統計
-
建構整合性軟體工具，解密代謝物
1150801~1160731
-
建構整合性軟體工具，解密代謝物
1140801~1150731
-
應用資料探勘於蛋白質後轉譯修飾分析：實現精準醫療的前沿探索
1130801~1140731
[液相層析串聯式質譜儀、蛋白質體、蛋白質後轉譯修飾、資料探勘 , LC-MS/MS, proteomics, protein post-translational modification, data mining] -
建構精準代謝物液相層析質譜圖銀行系統
1120801~1130930
[代謝體學,液相層析質譜儀,代謝物鑑定,代謝物定量,生物標記物探索 , metabolomics,liquid chromatography coupled with tandem mass spectrometer,metabolite quantitation,metabolite identification,biomarker discovery] -
蛋白質後轉譯修飾之自動探測平台建置
1110801~1120731
[蛋白質體學,液相層析串聯式質譜儀,後轉譯修飾 , proteomics,liquid chromatography coupled with mass spectrometer,post-translational modification] -
強化開源蛋白質定序軟體於商用軟體中之應用
1110101~1110731
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics] -
強化開源蛋白質定序軟體於商用軟體中之應用
1100101~1101231
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]
期刊著作
-
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
Clinical Proteomics, 20, 1, 2023-12-01
[ Biomarkers,Prediction,Proteomics,Rheumatoid arthritis,Treatment response ] -
Implementing the MSFragger Search Engine as a Node in Proteome Discoverer
Journal of Proteome Research, 22, 2, 520-525, 2023-02-03
[ liquid chromatography coupled to tandem mass spectrometry,Proteome Discoverer,proteomics ] -
Comparative Evaluation of Proteome Discoverer and FragPipe for the TMT-Based Proteome Quantification
Journal of Proteome Research, 21, 12, 3007-3015, 2022-12-02
[ FragPipe,labeled quantitative proteomics,mass spectrometry,Proteome Discoverer,tandem mass tag ] -
Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis
Clinica Chimica Acta, 536, 45-55, 2022-11-01
[ Biomarker,Encapsulating peritoneal sclerosis,microRNA,Peritoneal dialysis ] -
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
Cancer Cell, 39, 3, 361-379.e16, 2021-03-08
[ CDK inhibitor,combination immune checkpoint blockade,CPTAC,EGFR mAb,HNSCC,immune evasion,immunotherapy,predictive biomarker,proteogenomics,proteomics ] -
A Practical Guide to Metabolomics Software Development
Analytical Chemistry, 93, 4, 1912-1923, 2021-02-02 -
Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
Nature Communications, 11, 1, 2020-12-01 -
Philosopher: a versatile toolkit for shotgun proteomics data analysis
Nature Methods, 17, 9, 869-870, 2020-09-01 -
Crystal-C: A Computational Tool for Refinement of Open Search Results
Journal of Proteome Research, 19, 6, 2511-2515, 2020-06-05
[ LC-MS,liquid chromatography coupled to mass spectrometry,open search,peptide identification,post-translational modifications ] -
Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
Cell, 179, 4, 964-983.e31, 2019-10-31
[ ccRCC,chromosomal translocation,CPTAC,drug targets,immune infiltration,phosphoproteomics,proteogenomics,proteomics,renal carcinoma,tumor microenvironment ] -
ITop-Q: An Intelligent Tool for Top-down Proteomics Quantitation Using DYAMOND Algorithm
Analytical Chemistry, 89, 24, 13128-13136, 2017-12-19 -
MAGIC-web: a platform for untargeted and targeted N-linked glycoprotein identification
Nucleic Acids Research, 44, W1, W575-W580, 2016-07-08 -
IMet-Q: A user-friendly tool for label-free metabolomics quantitation using dynamic peak-width determination
PLoS ONE, 11, 1, 2016-01-01 -
Informatics View on the Challenges of Identifying Missing Proteins from Shotgun Proteomics
Journal of Proteome Research, 14, 12, 5396-5407, 2015-12-04
[ in silico digestion,missing proteins,olfactory receptors,sequence variation,unique peptide ] -
Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information
Analytical Chemistry, 87, 4, 2143-2151, 2015-02-17 -
Identification of tyrosine-phosphorylated proteins associated with lung cancer metastasis using label-free quantitative analyses
Journal of Proteome Research, 9, 8, 4102-4112, 2010-08-06
[ immunoaffinity enrichment,label-free quantitative analysis,lung cancer metastasis,mass spectrometry,tyrosine phosphorylation ]
研討會著作
-
Machine Learning Algorithms for ccRCC Data Analysis
203-206, 2022-01-01
[ ccRCC,Data Analysis,Machine Learning ] -
A novel peak alignment method for LC-MS data analysis using cluster-based techniques
525-530, 2010-12-01
校內獲獎
- 111 新進教師補助
- 111 新聘傑出獎(舊制)
- 110 新聘傑出獎(舊制)
- 109 新聘傑出獎(舊制)
著作審查：
-
111 ~ 111
IEEE Journal of Biomedical and Health Informatics
ISSN 2168-2194 EISSN 2168-2208
受邀擔任審稿者，審查一篇投稿文章 -
111 ~ 111
IEEE Computational Intelligence Magazine
ISSN 1556-603X EISSN 1556-6048
受邀擔任審稿者，審查一份投稿文章 -
111 ~ 111
IEEE Computational Intelligence Magazine
ISSN 1556-603X EISSN 1556-6048
受邀擔任 reviewer, 審查一篇投稿文章
- 偵測轉譯後修飾之方法、系統及電腦可讀取媒體 [中華民國]