國立中央大學教師履歷平台

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中文姓名

張彙音

英文姓名

Chang Hui-Yin

電子郵件

dr.chuiyin@gmail.com

proteomics 蛋白質體學代謝體學生物資訊學資料探勘 bioinformatics metabolomics rheumatoid arthritis 液相層析串聯式質譜儀 data mining

現職	國立中央大學生醫理工學院生醫科學與工程學系助理教授國立中央大學國際事務處組長
專長	生物資訊學資料探勘蛋白質體學代謝體學 Bioinformatics data mining proteomics metabolomics
專長簡述	生物資訊學、資料探勘、蛋白質體學, 代謝體學
最高學歷	國立陽明大學生物醫學資訊研究所博士
相關連結	個人網頁 GRB資訊系統

科技部學門領域	B - 生命科學 E - 工程及應用科學 E41 - 智慧計算(資訊) E4108 - 生物資訊與醫療資訊
政府GRB研究專長領域	1 - 理 15 - 生物科學 3 - 電信/資訊/原子能工程 3M - 資訊科學--軟體
教育部學門領域	5 - 工程、製造及營造 52 - 工程學門 5211 - 生醫工程學類

高教深耕計畫

應用精準醫療模式於類風濕疾病成因探討、共病關係與用藥關係
1130101~1131231
[類風溼性關節炎,精準醫療,機器學習,蛋白質體學 , rheumatoid arthritis,precision medicine,machine learning,proteomics]
新進/年輕教師學術研究補助-張彙音
1110101~1111231

國科會計畫統計

應用資料探勘於蛋白質後轉譯修飾分析：實現精準醫療的前沿探索
1130801~1140731
建構精準代謝物液相層析質譜圖銀行系統
1120801~1130930
[代謝體學,液相層析質譜儀,代謝物鑑定,代謝物定量,生物標記物探索 , metabolomics,liquid chromatography coupled with tandem mass spectrometer,metabolite quantitation,metabolite identification,biomarker discovery]
蛋白質後轉譯修飾之自動探測平台建置
1110801~1120731
[蛋白質體學,液相層析串聯式質譜儀,後轉譯修飾 , proteomics,liquid chromatography coupled with mass spectrometer,post-translational modification]
強化開源蛋白質定序軟體於商用軟體中之應用
1110101~1110731
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]
強化開源蛋白質定序軟體於商用軟體中之應用
1100101~1101231
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]

期刊著作

Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
Clinical Proteomics, 20, 1, 2023-12-01
[ Biomarkers,Prediction,Proteomics,Rheumatoid arthritis,Treatment response ]
Implementing the MSFragger Search Engine as a Node in Proteome Discoverer
Journal of Proteome Research, 22, 2, 520-525, 2023-02-03
[ liquid chromatography coupled to tandem mass spectrometry,Proteome Discoverer,proteomics ]
Comparative Evaluation of Proteome Discoverer and FragPipe for the TMT-Based Proteome Quantification
Journal of Proteome Research, 21, 12, 3007-3015, 2022-12-02
[ FragPipe,labeled quantitative proteomics,mass spectrometry,Proteome Discoverer,tandem mass tag ]
Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis
Clinica Chimica Acta, 536, 45-55, 2022-11-01
[ Biomarker,Encapsulating peritoneal sclerosis,microRNA,Peritoneal dialysis ]
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
Cancer Cell, 39, 3, 361-379.e16, 2021-03-08
[ CDK inhibitor,combination immune checkpoint blockade,CPTAC,EGFR mAb,HNSCC,immune evasion,immunotherapy,predictive biomarker,proteogenomics,proteomics ]
A Practical Guide to Metabolomics Software Development
Analytical Chemistry, 93, 4, 1912-1923, 2021-02-02
Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
Nature Communications, 11, 1, 2020-12-01
Philosopher: a versatile toolkit for shotgun proteomics data analysis
Nature Methods, 17, 9, 869-870, 2020-09-01
Crystal-C: A Computational Tool for Refinement of Open Search Results
Journal of Proteome Research, 19, 6, 2511-2515, 2020-06-05
[ LC-MS,liquid chromatography coupled to mass spectrometry,open search,peptide identification,post-translational modifications ]
Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
Cell, 179, 4, 964-983.e31, 2019-10-31
[ ccRCC,chromosomal translocation,CPTAC,drug targets,immune infiltration,phosphoproteomics,proteogenomics,proteomics,renal carcinoma,tumor microenvironment ]
ITop-Q: An Intelligent Tool for Top-down Proteomics Quantitation Using DYAMOND Algorithm
Analytical Chemistry, 89, 24, 13128-13136, 2017-12-19
MAGIC-web: a platform for untargeted and targeted N-linked glycoprotein identification
Nucleic Acids Research, 44, W1, W575-W580, 2016-07-08
IMet-Q: A user-friendly tool for label-free metabolomics quantitation using dynamic peak-width determination
PLoS ONE, 11, 1, 2016-01-01
Informatics View on the Challenges of Identifying Missing Proteins from Shotgun Proteomics
Journal of Proteome Research, 14, 12, 5396-5407, 2015-12-04
[ in silico digestion,missing proteins,olfactory receptors,sequence variation,unique peptide ]
Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information
Analytical Chemistry, 87, 4, 2143-2151, 2015-02-17
Identification of tyrosine-phosphorylated proteins associated with lung cancer metastasis using label-free quantitative analyses
Journal of Proteome Research, 9, 8, 4102-4112, 2010-08-06
[ immunoaffinity enrichment,label-free quantitative analysis,lung cancer metastasis,mass spectrometry,tyrosine phosphorylation ]

研討會著作

Machine Learning Algorithms for ccRCC Data Analysis
203-206, 2022-01-01
[ ccRCC,Data Analysis,Machine Learning ]
A novel peak alignment method for LC-MS data analysis using cluster-based techniques
525-530, 2010-12-01

高教深耕計畫

應用精準醫療模式於類風濕疾病成因探討、共病關係與用藥關係 1130101~1131231 [類風溼性關節炎,精準醫療,機器學習,蛋白質體學 , rheumatoid arthritis,precision medicine,machine learning,proteomics]

新進/年輕教師學術研究補助-張彙音 1110101~1111231

國科會計畫統計

應用資料探勘於蛋白質後轉譯修飾分析：實現精準醫療的前沿探索 1130801~1140731

蛋白質後轉譯修飾之自動探測平台建置 1110801~1120731 [蛋白質體學,液相層析串聯式質譜儀,後轉譯修飾 , proteomics,liquid chromatography coupled with mass spectrometer,post-translational modification]

強化開源蛋白質定序軟體於商用軟體中之應用 1110101~1110731 [蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]

強化開源蛋白質定序軟體於商用軟體中之應用 1100101~1101231 [蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]

期刊著作

Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop? Clinical Proteomics, 20, 1, 2023-12-01 [ Biomarkers,Prediction,Proteomics,Rheumatoid arthritis,Treatment response ]

Implementing the MSFragger Search Engine as a Node in Proteome Discoverer Journal of Proteome Research, 22, 2, 520-525, 2023-02-03 [ liquid chromatography coupled to tandem mass spectrometry,Proteome Discoverer,proteomics ]

Comparative Evaluation of Proteome Discoverer and FragPipe for the TMT-Based Proteome Quantification Journal of Proteome Research, 21, 12, 3007-3015, 2022-12-02 [ FragPipe,labeled quantitative proteomics,mass spectrometry,Proteome Discoverer,tandem mass tag ]

Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis Clinica Chimica Acta, 536, 45-55, 2022-11-01 [ Biomarker,Encapsulating peritoneal sclerosis,microRNA,Peritoneal dialysis ]

A Practical Guide to Metabolomics Software Development Analytical Chemistry, 93, 4, 1912-1923, 2021-02-02

Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors Nature Communications, 11, 1, 2020-12-01

Philosopher: a versatile toolkit for shotgun proteomics data analysis Nature Methods, 17, 9, 869-870, 2020-09-01

Crystal-C: A Computational Tool for Refinement of Open Search Results Journal of Proteome Research, 19, 6, 2511-2515, 2020-06-05 [ LC-MS,liquid chromatography coupled to mass spectrometry,open search,peptide identification,post-translational modifications ]

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma Cell, 179, 4, 964-983.e31, 2019-10-31 [ ccRCC,chromosomal translocation,CPTAC,drug targets,immune infiltration,phosphoproteomics,proteogenomics,proteomics,renal carcinoma,tumor microenvironment ]

ITop-Q: An Intelligent Tool for Top-down Proteomics Quantitation Using DYAMOND Algorithm Analytical Chemistry, 89, 24, 13128-13136, 2017-12-19

MAGIC-web: a platform for untargeted and targeted N-linked glycoprotein identification Nucleic Acids Research, 44, W1, W575-W580, 2016-07-08

IMet-Q: A user-friendly tool for label-free metabolomics quantitation using dynamic peak-width determination PLoS ONE, 11, 1, 2016-01-01

Informatics View on the Challenges of Identifying Missing Proteins from Shotgun Proteomics Journal of Proteome Research, 14, 12, 5396-5407, 2015-12-04 [ in silico digestion,missing proteins,olfactory receptors,sequence variation,unique peptide ]

Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information Analytical Chemistry, 87, 4, 2143-2151, 2015-02-17

研討會著作

Machine Learning Algorithms for ccRCC Data Analysis 203-206, 2022-01-01 [ ccRCC,Data Analysis,Machine Learning ]

A novel peak alignment method for LC-MS data analysis using cluster-based techniques 525-530, 2010-12-01

應用精準醫療模式於類風濕疾病成因探討、共病關係與用藥關係
1130101~1131231
[類風溼性關節炎,精準醫療,機器學習,蛋白質體學 , rheumatoid arthritis,precision medicine,machine learning,proteomics]

新進/年輕教師學術研究補助-張彙音
1110101~1111231

應用資料探勘於蛋白質後轉譯修飾分析：實現精準醫療的前沿探索
1130801~1140731

蛋白質後轉譯修飾之自動探測平台建置
1110801~1120731
[蛋白質體學,液相層析串聯式質譜儀,後轉譯修飾 , proteomics,liquid chromatography coupled with mass spectrometer,post-translational modification]

強化開源蛋白質定序軟體於商用軟體中之應用
1110101~1110731
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]

強化開源蛋白質定序軟體於商用軟體中之應用
1100101~1101231
[蛋白質體學,液相層析串聯式質譜儀,蛋白質定序,生物資訊 , Proteomics,Liquid chromatography coupled with mass spectrometry,protein identification,bioinformatics]

Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
Clinical Proteomics, 20, 1, 2023-12-01
[ Biomarkers,Prediction,Proteomics,Rheumatoid arthritis,Treatment response ]

Implementing the MSFragger Search Engine as a Node in Proteome Discoverer
Journal of Proteome Research, 22, 2, 520-525, 2023-02-03
[ liquid chromatography coupled to tandem mass spectrometry,Proteome Discoverer,proteomics ]

Comparative Evaluation of Proteome Discoverer and FragPipe for the TMT-Based Proteome Quantification
Journal of Proteome Research, 21, 12, 3007-3015, 2022-12-02
[ FragPipe,labeled quantitative proteomics,mass spectrometry,Proteome Discoverer,tandem mass tag ]

Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis
Clinica Chimica Acta, 536, 45-55, 2022-11-01
[ Biomarker,Encapsulating peritoneal sclerosis,microRNA,Peritoneal dialysis ]

A Practical Guide to Metabolomics Software Development
Analytical Chemistry, 93, 4, 1912-1923, 2021-02-02

Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
Nature Communications, 11, 1, 2020-12-01

Philosopher: a versatile toolkit for shotgun proteomics data analysis
Nature Methods, 17, 9, 869-870, 2020-09-01

Crystal-C: A Computational Tool for Refinement of Open Search Results
Journal of Proteome Research, 19, 6, 2511-2515, 2020-06-05
[ LC-MS,liquid chromatography coupled to mass spectrometry,open search,peptide identification,post-translational modifications ]

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
Cell, 179, 4, 964-983.e31, 2019-10-31
[ ccRCC,chromosomal translocation,CPTAC,drug targets,immune infiltration,phosphoproteomics,proteogenomics,proteomics,renal carcinoma,tumor microenvironment ]

ITop-Q: An Intelligent Tool for Top-down Proteomics Quantitation Using DYAMOND Algorithm
Analytical Chemistry, 89, 24, 13128-13136, 2017-12-19

MAGIC-web: a platform for untargeted and targeted N-linked glycoprotein identification
Nucleic Acids Research, 44, W1, W575-W580, 2016-07-08

IMet-Q: A user-friendly tool for label-free metabolomics quantitation using dynamic peak-width determination
PLoS ONE, 11, 1, 2016-01-01

Informatics View on the Challenges of Identifying Missing Proteins from Shotgun Proteomics
Journal of Proteome Research, 14, 12, 5396-5407, 2015-12-04
[ in silico digestion,missing proteins,olfactory receptors,sequence variation,unique peptide ]

Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information
Analytical Chemistry, 87, 4, 2143-2151, 2015-02-17

Machine Learning Algorithms for ccRCC Data Analysis
203-206, 2022-01-01
[ ccRCC,Data Analysis,Machine Learning ]

A novel peak alignment method for LC-MS data analysis using cluster-based techniques
525-530, 2010-12-01