國立中央大學教師履歷平台

期刊著作

• Circadian rest-activity rhythm in patients with narcolepsy following modafinil treatment: Outcomes and predictive markers
  Sleep Medicine, 139, 2026-03-01
  [ Actigraphy,Circadian rhythm,Modafinil,Narcolepsy,Nocturnal sleep-onset rapid eye movement period,Non-parametric analysis ]

• Implication of heart rhythm complexity in predicting long-term outcomes in pulmonary hypertension
  Journal of the Formosan Medical Association, 124, 9, 852-857, 2025-09-01
  [ Heart rate variability,Heart rhythm complexity,Pulmonary hypertension ]

• The prognosis of patients with myocardial infarction after light therapy: A preliminary study
  Biomedical Journal, 48, 3, 2025-06-01
  [ Actigraphy,Light therapy,Myocardial infarction,Sleep,Vitamin D ]

• ECG-based machine learning model for AF identification in patients with first ischemic stroke
  International Journal of Stroke, 20, 4, 411-418, 2025-04-01
  [ acute,antithrombotic,Asia,prevention,Risk factors,stroke ]

• Optimizing treatment of the novel intra-oral negative pressure for obstructive sleep apnea
  Sleep and Breathing, 29, 1, 2025-03-01
  [ Intra-oral negative pressure therapy (OPT),Sleep-disordered breathing,Titration,Upper airway physiology ]

• The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study
  Journal of Medical Internet Research, 27, 2025-01-01
  [ actigraphy,activity,circadian rhythm,heart rate variability,myocardial infarction,nonparametric analysis,prognosis,sleep ]

• Rest-Activity Rhythm Patterns and Their Associations With Depression and Obesity: A Study Using Actigraphy and Human-Smartphone Interactions
  Depression and Anxiety, 2025, 2025-01-01
  [ actigraphy,circadian rhythm,depression,digital phenotyping,human–smartphone interaction,obesity ]

• The optimal measurement period of actigraphy for circadian rhythm in relation to adiposity: A retrospective case-control study
  Sleep Medicine, 122, 1-7, 2024-10-01
  [ Actigraphy,Body composition,Circadian rhythm,Obesity,Relative amplitude,Rest-activity rhythms ]

• Diagnostic Potential of Combined Photoplethysmography and Ankle-Brachial Index in Peripheral Arterial Disease: A Duplex Ultrasonography-Based Comparative Study
  Journal of the American Heart Association, 13, 19, 2024-10-01
  [ ankle‐brachial index,duplex ultrasonography,peripheral arterial disease,photoplethysmography,toe‐brachial index ]

• Psychomotor Symptoms, Cognitive Impairments, and Suicidal Thoughts after COVID-19 Infection: A Case Report and Possible Allostatic Mechanism
  Annals of Geriatric Medicine and Research, 28, 3, 370-374, 2024-09-01
  [ Aged,Allostasis,COVID brain fog,COVID-19,Post-acute COVID-19 syndrome ]

• Post-traumatic Transient Neurological Dysfunction: A Proposal for Pathophysiology
  Journal of Neurotrauma, 41, 13-14, e1697-e1709, 2024-07-01
  [ cortical spreading depression,migraine,spreading depolarization,transient neurological dysfunction,traumatic brain injury ]

• Effects of modafinil on nocturnal sleep patterns in patients with narcolepsy: A cohort study
  Sleep Medicine, 119, 95-102, 2024-07-01
  [ Actigraphy,Modafinil,Narcolepsy,Nighttime awakening,Sleep disturbance ]

• Developing Methods for Assessing Mental Activity Using Human-Smartphone Interactions: Comparative Analysis of Activity Levels and Phase Patterns in General Mental Activities, Working Mental Activities, and Physical Activities
  Journal of Medical Internet Research, 26, 2024-06-17
  [ digital phenotyping,human-smartphone interaction,labor or leisure,machine learning,mental activity,physical activity ]

• Comparing Human-Smartphone Interactions and Actigraphy Measurements for Circadian Rhythm Stability and Adiposity: Algorithm Development and Validation Study
  Journal of Medical Internet Research, 26, 2024-06-05
  [ actigraphy,body composition,circadian rhythm,human-smartphone interaction,interdaily stability,obesity ]

• Rest-Activity Rhythm Differences in Acute Rehabilitation Between Poststroke Patients and Non–Brain Disease Controls: Comparative Study
  Journal of Medical Internet Research, 26, 1, 2024-01-01
  [ circadian rhythms,delirium screening,interdaily stability,relative amplitude,rest-activity rhythms,stroke rehabilitation ]

• Autonomic modulation by SGLT2i or DPP4i in patients with diabetes favors cardiovascular outcomes as revealed by skin sympathetic nerve activity
  Frontiers in Pharmacology, 15, 2024-01-01
  [ autonomic modulation,entropy analysis,NeuECG,skin sympathetic nerve activity,sodium-glucose cotransporter 2 inhibitor ]

• Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction
  Scientific Reports, 13, 1, 2023-12-01

• Characterization and identification of atrial fibrillation drivers in patients with nonparoxysmal atrial fibrillation using simultaneous amplitude frequency electrogram transform
  Journal of Cardiovascular Electrophysiology, 34, 3, 536-545, 2023-03-01
  [ Hilbert–Huang transform,nonparoxysmal atrial fibrillation,SAFE-T,similarity index,temporal frequency analysis ]

• A review of technological developments in lipid nanoparticle application for mRNA vaccination
  Human Vaccines and Immunotherapeutics, 19, 2, 2023-01-01
  [ COVID-19,journal analysis,Lipid nanoparticle (LNP),mRNA vaccine,patent landscape ]

• Examining Human-Smartphone Interaction as a Proxy for Circadian Rhythm in Patients With Insomnia: Cross-Sectional Study
  Journal of Medical Internet Research, 25, 1, 2023-01-01
  [ actigraphy,circadian rhythm,digital biomarkers,human-smartphone interaction,insomnia,intradaily variability,mobile apps ]

• Improvement in vocal-cord visualization with Trachway video intubating stylet using direct oxygen flow and effective analysis of the fraction of inspired oxygen: a bench study
  Journal of Clinical Monitoring and Computing, 36, 6, 1723-1730, 2022-12-01
  [ Fraction of inspired oxygen,Intubation,Oxygen delivery device,Trachway stylet ]

• Alterations of sympathetic dynamics after atrial fibrillation ablation by analysis sympathetic nerve activity provide prognostic value for recurrence and mechanistic insights into ablation
  Frontiers in Cardiovascular Medicine, 9, 2022-11-30
  [ atrial fibrillation,catheter ablation,cryoablation,neuECG,skin sympathetic nerve activity ]

• Identification of Patients with Potential Atrial Fibrillation during Sinus Rhythm Using Isolated P Wave Characteristics from 12-Lead ECGs
  Journal of Personalized Medicine, 12, 10, 2022-10-01
  [ atrial fibrillation,cardiovascular disease diagnosis,empirical mode decomposition,impulse noise,inter-lead dispersion,machine learning,physiological time series,signal processing,spike ]

• From Bench to Bedside: Clinical and Biomedical Investigations on Hepatitis C Virus (HCV) Genotypes and Risk Factors for Albuminuria
  Bioengineering, 9, 10, 2022-10-01
  [ albuminuria,chronic kidney disease (CKD),hepatitis C virus (HCV) genotype,National Health and Nutrition Examination Survey (NHANES),nephropathies,proteinuria ]

• Thermodynamic Interpretation of a Machine-Learning-Based Response Surface Model and Its Application to Pharmacodynamic Synergy between Propofol and Opioids
  Mathematics, 10, 10, 2022-05-01

• Preserved Electroencephalogram Power and Global Synchronization Predict Better Neurological Outcome in Sudden Cardiac Arrest Survivors
  Frontiers in Physiology, 13, 2022-04-20

• Overview of international health data governance in 2021 2021年國際健康數據治理概況
  Taiwan Journal of Public Health, 41, 1, 7-15, 2022-02-01
  [ data democratization,data governance,data sharing,health data,privacy protection ]

• The Subjective and Objective Improvement of Non-Invasive Treatment of Schumann Resonance in Insomnia—A Randomized and Double-Blinded Study
  Nature and Science of Sleep, 14, 1113-1124, 2022-01-01
  [ effectiveness,insomnia,polysomnography,questionnaire,Schumann resonance ]

• Probing penile hemodynamics by using photoplethysmography as objective indicators for male erection quality and sexual function
  Scientific Reports, 11, 1, 2021-12-01

• Strong Early Phase Parasympathetic Inhibition Followed by Sympathetic Withdrawal During Propofol Induction: Temporal Response Assessed by Wavelet-Based Spectral Analysis and Photoplethysmography
  Frontiers in Physiology, 12, 2021-09-13
  [ autonomic nervous system,heart rate variability,propofol anesthesia,pulse photoplethysmography,wavelet-based spectral analysis ]

• Different circadian rest-active rhythms in Kleine-Levin syndrome: A prospective and case-control study
  Sleep, 44, 9, 2021-09-01
  [ actigraphy,circadian rhythm,detrended fluctuation analysis,hypersomnia,Kleine-Levin syndrome ]

• White Matter Integrity Underlies the Physical-Cognitive Correlations in Subjective Cognitive Decline
  Frontiers in Aging Neuroscience, 13, 2021-08-02
  [ actigraphy,cognitive performance,community-dwelling older adults,diffusion tension imaging,mediation effects,physical activity,subjective cognitive decline,white matter ]

• Daily rhythm of fractal cardiac dynamics links to weight loss resistance: interaction with clock 3111t/c genetic variant
  Nutrients, 13, 7, 2021-07-01
  [ Autonomic function,Circadian rhythm,Dietary intervention,Fractal cardiac dynamics,Obesity treatment,Weight control ]

• Optimal substrate modification strategies using catheter ablation in patients with persistent atrial fibrillation: 3-year follow-up outcomes
  Journal of Cardiovascular Electrophysiology, 32, 6, 1561-1571, 2021-06-01
  [ atrial tachycardia,persistent atrial fibrillation,phase map,pulmonary vein isolation,similarity index,substrate ]

• The value of heart rhythm complexity in identifying high-risk pulmonary hypertension patients
  Entropy, 23, 6, 2021-06-01
  [ Detrended fluctuation analysis,Heart rate variability,Multiscale entropy,Non-linear analysis,Pulmonary hypertension ]

• Efficacy of Patient-Specific Strategy: Catheter Ablation Strategy of Persistent Atrial Fibrillation Based on Morphological Repetitiveness by Periodicity and Similarity
  Circulation: Arrhythmia and Electrophysiology, 14, 5, 2021-05-01
  [ ablation,atrial fibrillation,electrogram,morbidity,recurrence ]

• Complex dynamics of skin sympathetic nerve activities as a prognostic predictor for critically ill patients
  Journal of the Formosan Medical Association, 120, 1, 660-667, 2021-01-01
  [ Skinsympathetic nerveactivity Heartratevariability Multi-scale fluctuation analysis ]

• Predicting ventricular tachyarrhythmia in patients with systolic heart failure based on texture features of the gray zone from contrast-enhanced magnetic resonance imaging
  Journal of Cardiology, 76, 6, 601-609, 2020-12-01
  [ Texture featuresGray zone heterogeneityMagnetic resonance imagingCongestive ]

• Usefulness of heart rhythm complexity in heart failure detection and diagnosis
  Scientific Reports, 10, 1, 2020-12-01

• Noninvasive Hemodynamic Profiles during Hemodialysis in Patients with and without Heart Failure
  CardioRenal Medicine, 10, 4, 243-256, 2020-07-01

• Probing age-related changes in cardio-respiratory dynamics by multimodal coupling assessment
  Chaos, 30, 3, 2020-03-01
  [ Adult; Aged; Aging; Arrhythmia, Sinus; Databases, Factual; ]

• Heart Rhythm Complexity Predicts Long-Term Cardiovascular Outcomes in Peritoneal Dialysis Patients: A Prospective Cohort Study
  Journal of the American Heart Association, 9, 2, 2020-01-21

• Complex dynamics of skin sympathetic nerve activities provides mechanistic insights into critical-illness and are prognostic predictors
  Journal of the Formosan Medical Association, 2020-01-01

• Development of an addiction index and delineation 15-year trends of illicit drugs from the Taiwan national drug enhancement database
  Journal of Psychiatric Research, 120, 131-136, 2020-01-01

• The critical role of respiratory sinus arrhythmia on temporal cardiac dynamics
  Journal of Applied Physiology, 127, 6, 1733-1741, 2019-12-12
  [ Congestive heart failure,Detrended fluctuation analysis,Heart rate variability,Multiscale entropy,Respiratory sinus arrhythmia ]

• Heart Rhythm Complexity Impairment in Patients with Pulmonary Hypertension
  Scientific Reports, 9, 1, 2019-12-01
  [ pulmonary hypertension, heart rate variability, nonlinear complexity analysis ]

• Robust Fetal Heart Beat Detection via R-Peak Intervals Distribution
  IEEE Transactions on Biomedical Engineering, 66, 12, 3310-3319, 2019-12-01
  [ Fetal electrocardiogram,fetal heart rate,fetal R-peak detection ]

• Alteration autonomic control of cardiac function during hemodialysis predict cardiovascular outcomes in end stage renal disease patients
  Scientific Reports, 9, 1, 2019-12-01

• Cloud-Based Artificial Intelligence System for Large-Scale Arrhythmia Screening
  Computer, 52, 11, 40-51, 2019-11-01

• Nocturnal heart rate variability moderates the association between sleep-wake regularity and mood in young adults
  Sleep, 42, 5, 2019-05-01

• Empirical Mode Decomposition and Monogenic Signal-Based Approach for Quantification of Myocardial Infarction From MR Images
  IEEE Journal of Biomedical and Health Informatics, 23, 2, 731-743, 2019-03-01
  [ Ensemble empirical mode decomposition , gray zone , infarct core , monogenic signal , myocardial infarction ]

• A Minimum Arclength Method for Removing Spikes in Empirical Mode Decomposition
  IEEE Access, 7, 13284-13294, 2019-01-01
  [ Adaptive filters,empirical mode decomposition,impulse noise,masking-EMD,mode splitting,spike ]

• The association between heart rhythm complexity and the severity of abdominal aorta calcification in peritoneal dialysis patients
  Scientific Reports, 8, 1, 2018-12-01

• Endo/epicardial mapping issues: Authors' reply
  Europace, 20, 9, 2018-09-01

• Heterogeneous distribution of substrates between the endocardium and epicardium promotes ventricular fibrillation in arrhythmogenic right ventricular dysplasia/cardiomyopathy
  Europace, 20, 3, 501-511, 2018-03-01

• Development of an automatic diagnostic algorithm for pediatric otitis media
  Otology and Neurotology, 39, 8, 1060-1065, 2018-01-01
  [ nfant; Male; Otitis Media; Otitis dia with Effusion; ]

• A novel noninvasive surface ECG analysis using interlead QRS dispersion in arrhythmogenic right ventricular cardiomyopathy
  PLoS ONE, 12, 8, 2017-08-01

• Serial heart rhythm complexity changes in patients with anterior wall ST segment elevation myocardial infarction
  Scientific Reports, 7, 2017-03-02

• The use of a novel signal analysis to identify the origin of idiopathic right ventricular outflow tract ventricular tachycardia during sinus rhythm: Simultaneous amplitude frequency electrogram transformation mapping
  PLoS ONE, 12, 3, 2017-03-01

• Exploring the abnormal modulation of the autonomic systems during nasal flow limitation in upper airway resistance syndrome by hilbert-huang transform
  Frontiers in Medicine, 4, SEP, 2017-01-01
  [ Daytime hypervagotony , Hilbert-Huang transform , Parasympathetic tone , Sleep , Upper-airway-resistance-syndrome ]

• Benefits of Atrial Substrate Modification Guided by Electrogram Similarity and Phase Mapping Techniques to Eliminate Rotors and Focal Sources Versus Conventional Defragmentation in Persistent Atrial Fibrillation
  JACC: Clinical Electrophysiology, 2, 6, 667-678, 2016-11-01
  [ ablation,atrial fibrillation,electrogram,rotor ]

• Shape collaborative representation with fuzzy energy based active contour model
  Engineering Applications of Artificial Intelligence, 56, 60-74, 2016-11-01
  [ Fuzzy energy,Image segmentation,Level set method,Shape collaborative representation,Shape prior,Shape sparse representation ]

• Probing the fractal pattern of heartbeats in drosophila pupae by visible optical recording system
  Scientific Reports, 6, 2016-08-18

• Simultaneous Amplitude Frequency Electrogram Transformation (SAFE-T) Mapping to Identify Ventricular Tachycardia Arrhythmogenic Potentials in Sinus Rhythm
  , 2, 4, 459-470, 2016-08-01
  [ arrhythmogenic potentials , catheter ablation , Hilbert-Huang transform , isthmus , ventricular tachycardia ]

• Heart rhythm complexity impairment in patients undergoing peritoneal dialysis
  Scientific Reports, 6, 2016-06-21

• Reversible heart rhythm complexity impairment in patients with primary aldosteronism
  Scientific Reports, 5, 2015-08-18

• Outlier-resilient complexity analysis of heartbeat dynamics
  Scientific Reports, 5, 2015-03-06

• A new method to derive fetal heart rate from maternal abdominal electrocardiogram: Monitoring fetal heart rate during cesarean section
  PLoS ONE, 10, 2, 2015-02-13
  [ Monitoring of fetal heart rate ]

• Symbolic entropy of the amplitude rather than the instantaneous frequency of EEG varies in dementia
  Entropy, 17, 2, 560-579, 2015-01-01
  [ Alzheimer's disease , EEG amplitude , Photic stimulation , Symbolic dynamics , Vascular dementia ]

• Resting respiratory sinus arrhythmia is related to longer hospitalization in mood-disordered repetitive suicide attempters
  , 16, 5, 323-333, 2015-01-01
  [ Affective disorders , Autonomic nervous system , Depression , Heart rate variability , Suicide ]

• Acoustic-integrated dynamic MR imaging for a patient with obstructive sleep apnea
  Magnetic Resonance Imaging, 33, 10, 1350-1352, 2015-01-01
  [ Acoustic , Magnetic resonance imaging , Obstructive sleep apnea , Snore ]

• Synchronized imaging and acoustic analysis of the upper airway in patients with sleep-disordered breathing
  Physiological Measurement, 35, 12, 2501-2512, 2014-12-01
  [ dynamic magnetic resonance imaging , retroglossal , retropalatal , Snoring , sound recording ]

• Nonlinear analysis of sensory organization test for subjects with unilateral vestibular dysfunction
  PLoS ONE, 9, 3, 2014-03-14
  [ Adult; Female; Humans; Male; Middle Aged; Postural Balance; ]

• Correlations between the signal complexity of cerebral and cardiac electrical activity: A multiscale entropy analysis
  PLoS ONE, 9, 2, 2014-02-03

• Multi-scale symbolic entropy analysis provides prognostic prediction in patients receiving extracorporeal life support
  , 18, 5, 2014-01-01

• The use of signal analyses of ventricular tachycardia electrograms to predict the response of antitachycardia pacing in patients with implantable cardioverter-defibrillators
  Journal of Cardiovascular Electrophysiology, 25, 4, 411-417, 2014-01-01
  [ antitachycardia pacing,electrogram,implantable cardioverter-defibrillator,signal analysis,ventricular tachycardia ]

• A new method to estimate the amplitude spectrum analysis of ventricular fibrillation during cardiopulmonary resuscitation
  , 84, 11, 1505-1511, 2013-11-01
  [ Amplitude spectrum analysis , Automated external defibrillator , Empirical mode decomposition , Least mean square , Ventricular fibrillation ]

• Prevalence, characteristics, mapping, and catheter ablation of potential rotors in nonparoxysmal atrial fibrillation
  Circulation: Arrhythmia and Electrophysiology, 6, 5, 851-858, 2013-10-01
  [ Atrial fibrillation,Atrium,Catheter ablation,Electrocardiography,Mapping ]

• Influence of Non-Alcoholic Fatty Liver Disease on Autonomic Changes Evaluated by the Time Domain, Frequency Domain, and Symbolic Dynamics of Heart Rate Variability
  PLoS ONE, 8, 4, 2013-04-23

• Nonlinear analysis of fibrillatory electrogram similarity to optimize the detection of complex fractionated electrograms during persistent atrial fibrillation
  Journal of Cardiovascular Electrophysiology, 24, 3, 280-289, 2013-03-01
  [ ablation,atrial fibrillation,complex fractionated atrial electrograms,dominant frequency,electrogram ]

• Central sleep apnea: Effects on stroke volume in heart failure
  American Journal of Respiratory and Critical Care Medicine, 187, 4, 340-341, 2013-02-15

• Novel assessment of temporal variation in fractionated electrograms using histogram analysis of local fractionation interval in patients with persistent atrial fibrillation
  , 5, 5, 949-956, 2012-10-01
  [ Atrial fibrillation , Catheter ablation , Electrophysiology mapping , Histogram , Left atrium ]

• Empirical mode decomposition based detrended sample entropy in electroencephalography for Alzheimer's disease
  Journal of Neuroscience Methods, 210, 2, 230-237, 2012-09-30
  [ Alzheimer's disease,Electroencephalography,Empirical mode decomposition,Sample entropy ]

• A new way to analyze resuscitation quality by reviewing automatic external defibrillator data
  Resuscitation, 83, 2, 171-176, 2012-02-01
  [ Auto-correlation function,Automated external defibrillator,Cardiopulmonary resuscitation,Empirical mode decomposition,Out-of-hospital cardiac arrest ]

• The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure-a pilot study of multiscale entropy
  PLoS ONE, 6, 4, 2011-04-22

• Acute increase of complexity in the neurocardiovascular dynamics following carotid stenting
  , 123, 3, 187-192, 2011-03-01
  [ Angioplasty & stenting , Carotid stenosis , Cerebral hemodynamics , Complexity , Heart rate variability ]

• The relationship between aminoterminal propeptide of type III procollagen and heart rate variability parameters in heart failure patients: A potential serum marker to evaluate cardiac autonomic control and sudden cardiac death
  Clinical Chemistry and Laboratory Medicine, 48, 12, 1821-1827, 2010-12-01
  [ collagen , extra-cellular matrix , heart failure , HRV ]

• A novel preprocessing method using hilbert huang transform for MALDI-TOF and SELDI-TOF mass spectrometry data
  PLoS ONE, 5, 8, 2010-10-21

• Detrended fluctuation analysis predicts successful defibrillation for out-of-hospital ventricular fibrillation cardiac arrest
  , 81, 3, 297-301, 2010-03-01
  [ Automated external defibrillator , Defibrillation , Electrocardiography , Fractal , Ventricular fibrillation ]

• The nonlinear and nonstationary properties in EEG signals: Probing the complex fluctuations by Hilbert-huang transform
  Advances in Adaptive Data Analysis, 1, 3, 461-482, 2009-07-01
  [ brain topography , coherence , dementia , EEG , Hilbert-Huang transform , interwave frequency , intrawave frequency modulation , nonlinear , Nonstationary , time frequency analysis ]