國立中央大學教師履歷平台

期刊著作

• Benefits of Steroid Injections into Paraspinous Muscles After Spinal Surgery in a Rat Paraspinal Muscle Retraction Model
  International Journal of Molecular Sciences, 26, 22, 2025-11-01
  [ lumbar surgery,muscle regeneration,paraspinous muscle,steroid ]

• Caloric Restriction Attenuated Nerve Damages Mediated Through SIRT-1—a Study Using Nerve Crush Injury Model in Rats
  Molecular Neurobiology, 62, 7, 8261-8278, 2025-07-01
  [ Caloric restriction,Dorsal root ganglion,Nerve crush,Nerve degeneration,Nerve regeneration,Paw skin,SIRT-1 ]

• Dual-mode recognition of tRNAPro isoacceptors by Toxoplasma gondii Prolyl-tRNA synthetase
  EMBO Reports, 26, 11, 2931-2944, 2025-06-10
  [ Aminoacyl-tRNA Synthetase,Halofuginone,Parasite,Protein Synthesis,Toxoplasmosis ]

• Melatonin Ameliorate neuroinflammation in activated microglia through the Aryl hydrocarbon-Nrf2 axis
  International Journal of Biological Sciences, 21, 9, 3917-3933, 2025-01-01
  [ Aryl hydrocarbon receptors,Melatonin,Microglia,Nrf2 ]

• Cooperative tumor inhibition by CpG-oligodeoxynucleotide and cyclic dinucleotide in head and neck cancer involves T helper cytokine and macrophage phenotype reprogramming
  Biomedicine and Pharmacotherapy, 181, 2024-12-01
  [ CpG-ODN,Cyclic dinucleotide,Head and neck cancer,Macrophage,STING,TLR9 ]

• Adaptation of a eukaryote-like ProRS to a prokaryote-like tRNAPro
  Nucleic Acids Research, 52, 12, 7158-7170, 2024-07-08

• Adaptive evolution: Eukaryotic enzyme's specificity shift to a bacterial substrate
  Protein Science, 33, 6, 2024-06-01
  [ aminoacyl-tRNA synthetase,halofuginone,identity element,protein synthesis,thermophilic bacterium,tRNA ]

• A naturally occurring mini-alanyl-tRNA synthetase
  Communications Biology, 6, 1, 2023-12-01

• Sequence-specific targeting of Caenorhabditis elegans C-Ala to the D-loop of tRNAAla
  Journal of Biological Chemistry, 299, 9, 2023-09-01
  [ aminoacyl-tRNA synthetase,Caenorhabditis elegans,coevolution,DNA-binding domain,translation,tRNA-binding domain ]

• Neuronal Death Caused by HMGB1-Evoked via Inflammasomes from Thrombin-Activated Microglia Cells
  International Journal of Molecular Sciences, 24, 16, 2023-08-01
  [ endoplasmic retinaculum stress,high-mobility group box chromosomal protein 1(HMGB-1),inflammasome,thrombin ]

• Thrombin-Induced Microglia Activation Modulated through Aryl Hydrocarbon Receptors
  International Journal of Molecular Sciences, 24, 14, 2023-07-01
  [ aryl hydrocarbon receptor,inflammation,microglia,neurodegenerative disorder,thrombin ]

• Recognition of tRNAHis in an RNase P-Free Nanoarchaeum
  Microbiology spectrum, 11, 2, 2023-03-01
  [ aminoacyl-TRNA synthetase,protein synthesis,RNase P,thermophilic archaeum,tRNA ]

• Induction of Immune Responses and Phosphatidylserine Exposure by TLR9 Activation Results in a Cooperative Antitumor Effect with a Phosphatidylserine-targeting Prodrug
  International Journal of Biological Sciences, 19, 9, 2648-2662, 2023-01-01
  [ Cancer immunotherapy,CpG-oligodeoxynucleotide,Immunogenic cell death,Phosphatidylserine-targeting prodrug,Toll-like receptor,Topoisomerase I inhibitor ]

• Human Thg1 displays tRNA-inducible GTPase activity
  Nucleic Acids Research, 50, 17, 10015-10025, 2022-09-23

• Gain of C-Ala enables AlaRS to target the L-shaped tRNAAla
  Nucleic Acids Research, 50, 4, 2190-2200, 2022-02-28

• Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress
  Cell Death and Disease, 13, 1, 2022-01-01

• Biotinylation of yeast histones and its characteristics
  Research Journal of Biotechnology, 16, 6, 162-169, 2021-06-01
  [ AMKM,Arc1p,Biotinylation,Bpl1p,Candida albicans,H2B,In vitro,In vivo,Saccharomyces cerevisiae ]

• Fission yeast Asc1 stabilizes the interaction between eukaryotic initiation factor 3a and Rps0A/uS2 for protein synthesis
  Molecular and Cellular Biology, 39, 19, 2019-10-01
  [ Aminoacyl-tRNA synthetase cofactor , Fission yeast , Multisynthetase complex ]

• Naturally occurring dual recognition of tRNAHis substrates with and without a universal identity element
  RNA Biology, 16, 9, 1275-1285, 2019-09-02
  [ Aminoacyl,Caenorhabditis elegans,identity element,protein synthesis,translation,tRNA,tRNA synthetase ]

• Functional Substitution of an Indirect Pathway for tRNA Glutaminylation with a Direct Pathway by T. thermophiles GlnRS
  IOP Conference Series: Earth and Environmental Science, 276, 1, 2019-06-03
  [ Aminoacyl-tRNA synthetases,Arc1p,Direct Pathway,GlnRS,Indirect Pathway ]

• Evolutionary gain of highly divergent tRNA specificities by two isoforms of human histidyl-tRNA synthetase
  Cellular and Molecular Life Sciences, 74, 14, 2663-2677, 2017-07-01
  [ Aminoacyl-tRNA synthetase,Evolution,Phylogenetic analysis,Protein synthesis,Subfunctionalization,tRNA ]

• The regulation of transcriptome responses in zebrafish embryo exposure to triadimefon
  Environmental Toxicology, 32, 1, 217-226, 2017-01-01
  [ RNA-seq , transcriptome , triadimefon , zebrafish ]

• Modulating the structure and function of an aminoacyl-trna synthetase cofactor by biotinylation
  Journal of Biological Chemistry, 291, 33, 17102-17111, 2016-08-12

• A WHEP domain regulates the dynamic structure and activity of Caenorhabditis elegans glycyl-tRNA synthetase
  Journal of Biological Chemistry, 291, 32, 16567-16575, 2016-08-05

• Vanderwaltozyma polyspora possesses two glycyl-tRNA synthetase genes: One constitutive and one inducible
  Fungal Genetics and Biology, 76, 47-56, 2015-03-01
  [ Aminoacyl-tRNA synthetase , Constitutive gene , Dual function , Inducible gene , Stress ]

• Divergent Alanyl-tRNA synthetase genes of Vanderwaltozyma polyspora descended from a common ancestor through whole-genome duplication followed by asymmetric evolution
  Molecular and Cellular Biology, 35, 13, 2242-2253, 2015-01-01

• Functional substitution of a eukaryotic glycyl-trna synthetase with an evolutionarily unrelated bacterial cognate enzyme
  PLoS ONE, 9, 4, 2014-04-17

• An insertion peptide in yeast glycyl-tRNA synthetase facilitates both productive docking and catalysis of cognate tRNAs
  Molecular and Cellular Biology, 33, 17, 3515-3523, 2013-09-11

• Trans-kingdom rescue of Gln-tRNAGln synthesis in yeast cytoplasm and mitochondria
  Nucleic Acids Research, 40, 18, 9171-9181, 2012-10-01

• Saccharomyces cerevisiae possesses a stress-inducible Glycyl-tRNA synthetase gene
  PLoS ONE, 7, 3, 2012-03-16

• Alanyl-tRNA synthetase genes of Vanderwaltozyma polyspora arose from duplication of a dual-functional predecessor of mitochondrial origin
  Nucleic Acids Research, 40, 1, 314-322, 2012-01-01

• Rescuing a dysfunctional homologue of a yeast glycyl-tRNA synthetase gene
  ACS Chemical Biology, 6, 11, 1182-1187, 2011-11-18

• A tryptophan-rich peptide acts as a transcription activation domain
  BMC Molecular Biology, 11, 2010-11-16

• A single sequence context cannot satisfy all non-AUG initiator codons in yeast
  BMC Microbiology, 10, 2010-07-13

• Schizosaccharomyces pombe possesses two paralogous valyl-tRNA synthetase genes of mitochondrial origin
  Molecular Biology and Evolution, 27, 6, 1415-1424, 2010-06-03
  [ Aminoacylation , Appended domain , Mitochondrial localization , TRNA binding , Valyl-tRNA synthetase ]

• Evolutionary basis of converting a bacterial tRNA synthetase into a yeast cytoplasmic or mitochondrial enzyme
  Journal of Biological Chemistry, 284, 36, 23954-23960, 2009-09-04

• Translational efficiency of redundant ACG initiator codons is enhanced by a favorable sequence context and remedial initiation
  Journal of Biological Chemistry, 284, 2, 818-827, 2009-01-09

• Promoting the formation of an active synthetase/tRNA complex by a nonspecific tRNA-binding domain
  Journal of Biological Chemistry, 283, 45, 30699-30706, 2008-11-07

• Translational efficiency of a non-AUG initiation codon is significantly affected by its sequence context in yeast
  Journal of Biological Chemistry, 283, 6, 3173-3180, 2008-02-08

• Cross-species and cross-compartmental aminoacylation of isoaccepting tRNAs by a class II tRNA synthetase
  Journal of Biological Chemistry, 281, 42, 31430-31439, 2006-10-20

• An unusual pattern of protein expression and localization of yeast alanyl-tRNA synthetase isoforms
  Molecular Microbiology, 60, 1, 189-198, 2006-04-01

• Redundancy of non-AUG initiators: A clever mechanism to enhance the efficiency of translation in yeast
  Journal of Biological Chemistry, 281, 12, 7775-7783, 2006-03-24

• Translation of a yeast mitochondrial tRNA synthetase initiated at redundant non-AUG codons
  Journal of Biological Chemistry, 279, 48, 49656-49663, 2004-11-26

• Translation Initiation from A Naturally Occurring Non-AUG Codon in Saccharomyces cerevisiae
  Journal of Biological Chemistry, 279, 14, 13778-13785, 2004-04-02

• Mitochondrial form of a tRNA synthetase can be made bifunctional by manipulating its leader peptide
  Biochemistry, 42, 6, 1646-1651, 2003-02-18

• A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria
  Proceedings of the National Academy of Sciences of the United States of America, 97, 25, 13743-13748, 2000-12-05

• Crystal structure of Trbp111: A structure-specific tRNA-binding protein
  EMBO Journal, 19, 23, 6287-6298, 2000-12-01
  [ Crystal structure , Oligonucleotide , Oligosaccharide-binding fold , RNA binding protein , tRNA synthetase ]

• Functional redundancy in the nonspecific RNA binding domain of a class I tRNA synthetase
  Journal of Biological Chemistry, 275, 22, 17180-17186, 2000-06-02

• Species barrier to RNA recognition overcome with nonspecific RNA binding domains
  Journal of Biological Chemistry, 274, 23, 16508-16512, 1999-06-04

• Getting tRNA synthetases into the nucleus
  Trends in Biochemical Sciences, 24, 4, 127-128, 1999-04-01

• Evolution of RNA-binding specificity in T4 DNA polymerase
  Journal of Biological Chemistry, 272, 28, 17703-17710, 1997-08-05

• Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment
  Proceedings of the National Academy of Sciences of the United States of America, 94, 15, 8042-8046, 1997-07-22
  [ Bacteriophage RB69 , Bacteriophage T4 , DNA polymerase , Replication fidelity ]

• Crystal structure of a pol α family replication DNA polymerase from bacteriophage RB69
  Cell, 89, 7, 1087-1099, 1997-01-01

• Determinants of T4 DNA polymerase function
  FASEB Journal, 10, 6, 1996-12-01

• Modular organization of T4 DNA polymerase. Evidence from phylogenetics
  Journal of Biological Chemistry, 270, 44, 26558-26564, 1995-01-01