國立中央大學教師履歷平台

教師個人簡歷 »

中文姓名

徐敬衡

英文姓名

Shu, Chin-Hang

電子郵件

chinshu@cc.ncu.edu.tw

Saccharomyces cerevisiae Agaricus blazei kinetics Molecular weight pH 生化工程 spent mushroom substrate Submerged culture Schizophyllum commune Antrodia camphorata Chlorella sp. Exopolysaccharides 2-Phenylethanol 醱酵工程生化反應槽設計 butanol charantin GABA co-digestion 共消化兩階段厭氧消化乾式發酵 Submerged fermentation temperature Tumor necrosis factor-α β-glucan Exopolysaccharide in situ product recovery Antrodia cinnamomea Polysaccharide Oil LED photo-bioreactor Light intensity Light wavelength Mixed culture

現職	國立中央大學工學院化學工程與材料工程學系教授
專長	醱酵工程生化反應槽設計生化工程
專長簡述	醱酵工程、生化反應槽設計、生化工程
最高學歷	美國The Ohio State University 化學工程學系博士
相關連結	個人網頁 GRB資訊系統

科技部學門領域	B302025 - 生物技術產業計畫 E - 工程及應用科學 E02 - 化學工程 E0202 - 生化及生醫工程 E0213 - 生化工程 E0220 - B類-生化及生醫工程 E0234 - 生化及生醫工程 E10 - 能源科技 E1010 - 燃料電池 E90 - 台電產業科技學術研究 E9010 - 環保化學
政府GRB研究專長領域	2 - 工 23 - 化學工程(含化工、石油工業、燃料工業) 2301 - 化學工程 2F - 能源工程 5 - 農 53 - 農業化學
教育部學門領域

國科會計畫統計

開發以奈米零價鐵於兩階段厭氧共消化技術轉化高固體菇包木屑廢棄物為氫氣與甲烷之研究
1120601~1130531
[開發以奈米零價鐵於兩階段厭氧共消化技術轉化高固體菇包木屑廢棄物為氫氣與甲烷之研究 , Research on the development of two-stage anaerobic co-digestion technology using nanoscale zero-valent iron to convert high-solid mushroom wood waste into hydrogen and methane]
開發以油茶果殼生物炭與兩階段厭氧共消化之乾式發酵技術來轉換菇包木屑廢料為甲烷之研究
1110601~1120531
[奈米零價鐵,兩階段厭氧消化,乾式發酵,共消化,高固體菇包木屑,氫氣與甲烷 , high-solid mushroom-coated sawdust,nano-zero valent iron,co-digestion,hydrogen and methane,two-stage]
開發混合特定功能菌株生產高GABA與低咖啡因之後發酵機能茶
1100801~1110731
[後發酵茶,γ-胺基丁酸,去咖啡因,乳酸菌,抗失眠 , post-fermentation tea,GABA,decaffeination,lactic acid bacteria,anti-insomnia]
開發以生物碳與兩階段厭氧共消化之乾式發酵技術來轉換農業廢棄物為甲烷之研究
1100601~1110531
[包木屑,兩階段厭氧消化,乾式發酵,共消化,生物炭 , spent mushroom substrate (SMS),two-stage anaerobic digestion,dry fermentation,co-digestion,biochar]
開發機能性有機蔬菜之發酵飲品
1090601~1100531
[十字花科,GABA,硫代葡萄糖苷（Glucosinolates）,活性發酵飲品,抗失眠,抗憂鬱 , Brassicaceae,GABA,Glucosinolates,functional vegetable juices,anti-insomnia,anti-depression]
利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性
1080601~1090531
[山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]
利用Cupriavidus necator轉化農業廢棄物中的木質素為香草酸之研究
1070801~1080731
[農業廢棄物,木質素,香草酸,鉤蟲貪銅菌 , Agricultural waste, lignin, vanillic acid, Cupriavidus necator]
藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究
1061101~1071031
[厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]
開發新型節能溫度感應海綿之萃取發酵於酵母菌生產香料苯乙醇之研究
1060801~1070731
[苯乙醇,萃取發酵,疏水PDMS 海綿,溫度感應,酵母菌 , 2-Phenylethanol, Saccharomyces cerevisiae, sponge extractive fermentation, temperature responsive]
以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株
1060601~1070531
[巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]
開發新型節能溫度感應疏水海棉之萃取式發酵槽於連續生產丁醇之研究
1050801~1060731
[疏水海綿, 萃取式發酵, 溫度感應高分子, 丁醇 , extractive fermentation, butanol, sponge, thermal responsive, poly-N-isopropylacrylamide]
開發新型疏水海綿萃取式發酵槽於發酵生產丁醇之研究
1040801~1050731
[extractive fermentation, butanol, sponge, PDMS ]

產學合作計畫統計

開發以奈米零價鐵於兩階段厭氧共消化技術轉化高固體菇包木屑廢棄物為氫氣與甲烷之研究
1120601~1130531
[菇包木屑,兩階段厭氧發酵,奈米零價鐵,生質能源 , spent mushroom substrate,Two-stage anaerobic digestion,Nanoscale Zero-Valent Iron,Bioenergy]
開發以油茶果殼生物炭與兩階段厭氧共消化之乾式發酵技術來轉換菇包木屑廢料為甲烷之研究
1110601~1120531
[菇包木屑,兩階段厭氧消化,乾式發酵,共消化,油茶果殼生物炭,生質能源 , Camellia Oleifera shell biochar,spent mushroom substrate,co-digestion,Bioenergy,two-stage]
開發以生物碳與兩階段厭氧共消化之乾式厭氧發酵技術來轉換農業廢棄物為甲烷之研究
1100601~1110531
[乾式厭氧發酵,生物碳,甲烷 , Dry anaerobic fermentation,Biochar,Methane]
開發機能性有機蔬菜之發酵飲品
1090601~1100531
[發酵,十字花科,乳酸菌 , fermentation,Brassicaceae,lactic acid bacteria]
利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性
1080601~1090531
[山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]
藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究
1061101~1071031
[厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]
以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株
1060601~1070531
[巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]
「台灣化學工程學會63週年慶祝大會」、「科技部化學工程學門成果發表會
1051124~1051126
2016第21屆生物技術暨生物工程國際研討會
1050301~1050625
第21屆生物技術暨生物工程國際研討會
1050301~1050625
第21屆生物技術與生化工程年會
1050301~1050625

期刊著作

Enhancing the bioconversion of ferulic acid from alkaline hydrolysate of corn cobs to vanillin by Amycolatopsis thermoflava under nutrient limitation and reducing sugar control
Journal of Chemical Technology and Biotechnology, 98, 1, 238-246, 2023-01-01
[ agro-waste,bioconversion,corn cobs,ferulic acid,vanillin ]
Improving bioactivities of Momordica charantia broth through fermentation using mixed cultures of Lactobacillus plantarum, Gluconacetobacter sp. and Saccharomyces cerevisiae
Process Biochemistry, 117, 142-152, 2022-06-01
[ Charantin,Coumarin,Momordica charantia,Xanthine oxidase inhibition ]
Enhancing Methane Production in a Two-Stage Anaerobic Digestion of Spent Mushroom Substrate and Chicken Manure via Activation of Sludge, Optimization of Temperature, and C/N Ratio
Frontiers in Environmental Science, 9, 2022-02-10
Enhanced butanol production by Clostridium acetobutylicum fermentation using thermo-responsive poly(N-isopropylacrylamide)-grafted PDMS sponge as adsorbent material
Journal of Chemical Technology and Biotechnology, 95, 1, 255-263, 2020-01-01
[ ABE fermentation , adsorption , butanol , Clostridium acetobutylicum , poly(N-isopropylacrylamide) , polydimethylsiloxane ]
Temperature control and in situ product recovery strategies to enhance the bioconversion of L-phenylalanine into 2-phenylethanol
Journal of Chemical Technology and Biotechnology, 2020-01-01
[ 2-phenylethanol,in situ product recovery,Saccharomyces cerevisiae,temperature control ]
Enhanced bioconversion of L-phenylalanine into 2-phenylethanol via an oxygen control strategy and in situ product recovery
Journal of Chemical Technology and Biotechnology, 93, 10, 3035-3043, 2018-10-01
[ 2-phenylethanol , in situ product recovery , oxygen control , PDMS sponge , Saccharomyces cerevisiae ]
Effects of light intensity and wavelength on the production of lactobionic acid from whey by Pseudomonas taetrolens in batch cultures
Journal of Chemical Technology and Biotechnology, 93, 6, 1595-1600, 2018-06-01
[ lactobionic acid , photoreceptor , Pseudomonas taetrolens , red and blue LED light , two stage LED bioreactor ]
Enhancing oil accumulation of a mixed culture of Chlorella sp. and Saccharomyces cerevisiae using fish waste hydrolysate
Journal of the Taiwan Institute of Chemical Engineers, 67, 377-384, 2016-10-01
[ Chlorella sp. , Fish waste hydrolysate , Mixed culture , Oil , Organic acids , Saccharomyces cerevisiae ]
Effects of red light and addition of monoterpenes and tangerine oil on the production of biomass and triterpenoids of Antrodia cinnamomea in submerged cultures
Journal of the Taiwan Institute of Chemical Engineers, 67, 140-147, 2016-10-01
[ Antrodia cinnamomea,Monoterpenes,Red light,Tangerine oil,Triterpenoids ]
Enhancing high quality oil accumulation and carbon dioxide fixation by a mixed culture of Chlorella sp. and Saccharomyces cerevisiae
Journal of the Taiwan Institute of Chemical Engineers, 44, 6, 936-942, 2013-11-01
[ Carbon dioxide , Chlorella sp. , Mixed culture , Oil , Saccharomyces cerevisiae ]
Effects of light quality on the accumulation of oil in a mixed culture of Chlorella sp. and Saccharomyces cerevisiae
Journal of Chemical Technology and Biotechnology, 87, 5, 601-607, 2012-05-01
[ Chlorella sp. , LED photo-bioreactor , Light quality , Lipid , Mixed-culture ]
Production of schizophyllan glucan by Schizophyllum commune ATCC 38548 from detoxificated hydrolysate of rice hull
Journal of the Taiwan Institute of Chemical Engineers, 42, 3, 387-393, 2011-05-01
[ Acetic acid , Dilute acid hydrolysate , Furfural , HMF , PH , Schizophyllum commune , Submerged culture ]
Effects of aeration rate on the production of ergosterol and blazeispirol A by Agaricus blazei in batch cultures
Journal of the Taiwan Institute of Chemical Engineers, 42, 2, 212-216, 2011-03-01
[ Aeration rate , Biochemical engineering , Bioprocesses , Fermentation ]
Effects of light intensity and light wavelength on the production of mycophenolic acid by Penicillium brevicompactum in batch cultures
Enzyme and Microbial Technology, 46, 6, 466-471, 2010-05-01
[ Light intensity , Light wavelength , Mycophenolic acid , Penicillium brevicompactum ]
Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo
Journal of Nutritional Biochemistry, 20, 10, 753-764, 2009-10-01
[ Agaricus blazei , Antitumor activity , Apoptosis , Human prostate cancer ]
Effects of light wavelength and intensity on the production of ethanol by Saccharomyces cerevisiae in batch cultures
Journal of Chemical Technology and Biotechnology, 84, 8, 1156-1162, 2009-07-27
[ Ethanol , LED photo-bioreactor , Light intensity , Light wavelength , Saccharomyces cerevisiae ]
Biochemical properties and expression profile of human prolyl dipeptidase DPP9
Archives of Biochemistry and Biophysics, 485, 2, 120-127, 2009-05-15
[ Dimerization , Dipeptidyl peptidase , DPP9 , Substrate specificity ]
Enhanced removal of dimethyl sulfide from a synthetic waste gas stream using a bioreactor inoculated with Microbacterium sp. NTUT26 and Pseudomonas putida
Journal of Industrial Microbiology and Biotechnology, 36, 1, 95-104, 2009-01-01
[ Biofiltration , Bioreactor , Dimethyl sulfide , Inoculation ]
Black soybean promotes the formation of active components with antihepatoma activity in the fermentation product of Agaricus blazei
Journal of Agricultural and Food Chemistry, 56, 20, 9447-9454, 2008-10-22
[ Agaricus blazei , Antihepatoma activity , Black soybean , Blazeiperol A , Blazeiperol C , Fermentation product , Fraction , Hep 3B cells , Hep G2 cells , Mycelia , Soybean ]
Effects of sodium chloride on the production of bioactive exopolysaccharides in submerged cultures of Phellinus linteus
Journal of Chemical Technology and Biotechnology, 83, 5, 618-624, 2008-05-01
[ Exopolysaccharides , Phellinus linteus , Sodium chloride , Submerged culture , Tumour necrosis factor α ]
Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged culture
Journal of the Chinese Institute of Chemical Engineers, 39, 1, 1-8, 2008-01-01
[ Antioxidant , Antrodia camphorata , pH , Phenolics , Polyaccharide , Submerged fermentation ]
Effects of culture temperature on the production of bioactive polysaccharides by Agaricus blazei in batch cultures
Journal of Chemical Technology and Biotechnology, 82, 9, 831-836, 2007-09-01
[ β-glucan , Agaricus blazei , Molecular weight , Polysaccharides , Temperature , Tumour necrosis factor-α ]
Medium optimization for producing bioactive exopolysaccharides by Agaricus brasiliensis S. Wasser et al. (=A. blazei Murrill ss. Heinem) in submerged culture
Food Technology and Biotechnology, 45, 3, 327-333, 2007-07-01
[ Agaricus blazei , Agaricus brasiliensis , Exopolysaccharides , Phosphate , Submerged culture , TNF-α ]
Production, purification and partial characterization of a novel endo-β-1,3-glucanase from Agaricus brasiliensis
Process Biochemistry, 41, 5, 1229-1233, 2006-05-01
[ Agaricus brasiliensis , Characterization , Endo-β-1,3-glucanase , Exopolysaccharides , Purification , Thermostable ]
Purification and partial characterization of a lipase from Antrodia cinnamomea
Process Biochemistry, 41, 3, 734-738, 2006-03-01
[ Antrodia cinnamomea , Lipase , Production , Purification ]
Effects of supplementation of succinic acid on the production and molecular weight distribution of exopolysaccharides by Antrodia camphorata in batch cultures
Journal of Chemical Technology and Biotechnology, 80, 2, 216-222, 2005-02-01
[ Air-lift bioreactor , Antrodia camphorata , Exopolysaccharide , Number average molecular weight , Succinic acid ]
Effects of morphology and oxygen supply on schizophyllan formation by Schizophyllum commune using a pellet size controlling bioreactor
Journal of Chemical Technology and Biotechnology, 80, 12, 1383-1388, 2005-01-01
[ Morphology , Pellet size control , Schizophyllan , Schizophyllum commune ]
Effects of culture pH on the production of bioactive polysaccharides by Agaricus blazei in batch cultures
Journal of Chemical Technology and Biotechnology, 79, 9, 998-1002, 2004-09-01
[ β-glucan , Agaricus blazei , Molecular weight , pH , Polysaccharide , Tumor necrosis factor-α ]
Effect of pH on the production and molecular weight distribution of exopolysaccharide by Antrodia camphorata in batch cultures
Process Biochemistry, 39, 8, 931-937, 2004-04-30
[ Antrodia camphorata , Exopolysaccharide , Molecular weight , pH , Submerged fermentation , Two-stage pH process ]
Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7.
Biotechnology Letters, 26, 4, 2061-2064, 2004-01-01
Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-α release capability of macrophage cell line RAW 264.7
Biotechnology Letters, 25, 24, 2061-2064, 2003-12-01
[ Agaricus blazei , Molecular weight , Polysaccharide , Quality control , Tumor necrosis factor-α ]
Enhanced shear protection and increased production of an anti-tumor polysaccharide by Agaricus blazei in xanthan-supplemented cultures
Biotechnology Letters, 25, 11, 873-876, 2003-06-01
[ Agaricus blazei , Anti-tumor polysaccharide , Shear protection , Stirred tank reactor , Xanthan ]
Effects of citric acid on cell growth and schizophyllan formation in the submerged culture of Schizophyllum commune
Journal of the Chinese Institute of Chemical Engineers, 33, 3, 315-320, 2002-07-01
[ Citric acid , Kinetics , Schizophyllan , Schizophyllum commune ]
Optimization of L-phenylalanine production of Corynebacterium glutamicum under product feedback inhibition by elevated oxygen transfer rate
Biotechnology and Bioengineering, 77, 2, 131-141, 2002-01-20
[ Corynebacterium glutamicum , Oxygen supply , Phenylalanine , Product inhibition ]
Kinetics and modeling of GM-CSF production by recombinant yeast in a three-phase fluidized bed bioreactor
Biotechnology and Bioengineering, 53, 5, 470-477, 1997-03-05
[ fluidized bed bioreactor , kinetics , modeling , recombinant , yeast ]
Effect of particle loading on GM-CSF production by Saccharomyces cerevisiae in a three-phase fluidized bed bioreactor
Biotechnology and Bioengineering, 51, 2, 229-236, 1996-07-20
[ bioreactor, fluidized bed , murine granulocyte-macrophage colony stimulating factor , Saccharomyces cerevisiae ]
Kinetics of continuous GM-CSF production by recombinant Saccharomyces cerevisiae in an airlift bioreactor
Journal of Biotechnology, 48, 1-2, 107-116, 1996-07-18
[ Air-lift bioreactor , GM-CSF , Kinetics , Saccharomyces cerevisiae ]
Kinetics and stability of GM-CSF production by recombinant yeast cells immobilized in a fibrous-bed bioreactor
Biotechnology Progress, 12, 4, 449-456, 1996-07-01
A substrate feeding strategy--using an oxystat for L-phenylalanine fermentation by Corynebacterium glutamicum
Biotechnology Techniques, 8, 11, 843-846, 1994-11-01
Kinetics and modeling of temperature effects on batch xanthan gum fermentation
Biotechnology and Bioengineering, 37, 6, 567-574, 1991-01-01
[ kinetics , model , temperature , xanthan fermentation ]
Effects of temperature on cell growth and xanthan production in batch cultures of Xanthomonas campestris
Biotechnology and Bioengineering, 35, 5, 454-468, 1990-01-01

專書

Bioprocessing for Value-Added Products from Renewable Resources
447-463, 2007-12-01

國科會計畫統計

開發混合特定功能菌株生產高GABA與低咖啡因之後發酵機能茶 1100801~1110731 [後發酵茶,γ-胺基丁酸,去咖啡因,乳酸菌,抗失眠 , post-fermentation tea,GABA,decaffeination,lactic acid bacteria,anti-insomnia]

開發以生物碳與兩階段厭氧共消化之乾式發酵技術來轉換農業廢棄物為甲烷之研究 1100601~1110531 [包木屑,兩階段厭氧消化,乾式發酵,共消化,生物炭 , spent mushroom substrate (SMS),two-stage anaerobic digestion,dry fermentation,co-digestion,biochar]

開發機能性有機蔬菜之發酵飲品 1090601~1100531 [十字花科,GABA,硫代葡萄糖苷（Glucosinolates）,活性發酵飲品,抗失眠,抗憂鬱 , Brassicaceae,GABA,Glucosinolates,functional vegetable juices,anti-insomnia,anti-depression]

利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性 1080601~1090531 [山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]

利用Cupriavidus necator轉化農業廢棄物中的木質素為香草酸之研究 1070801~1080731 [農業廢棄物,木質素,香草酸,鉤蟲貪銅菌 , Agricultural waste, lignin, vanillic acid, Cupriavidus necator]

藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究 1061101~1071031 [厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]

開發新型節能溫度感應海綿之萃取發酵於酵母菌生產香料苯乙醇之研究 1060801~1070731 [苯乙醇,萃取發酵,疏水PDMS 海綿,溫度感應,酵母菌 , 2-Phenylethanol, Saccharomyces cerevisiae, sponge extractive fermentation, temperature responsive]

以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株 1060601~1070531 [巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]

開發新型節能溫度感應疏水海棉之萃取式發酵槽於連續生產丁醇之研究 1050801~1060731 [疏水海綿, 萃取式發酵, 溫度感應高分子, 丁醇 , extractive fermentation, butanol, sponge, thermal responsive, poly-N-isopropylacrylamide]

開發新型疏水海綿萃取式發酵槽於發酵生產丁醇之研究 1040801~1050731 [extractive fermentation, butanol, sponge, PDMS ]

產學合作計畫統計

開發以奈米零價鐵於兩階段厭氧共消化技術轉化高固體菇包木屑廢棄物為氫氣與甲烷之研究 1120601~1130531 [菇包木屑,兩階段厭氧發酵,奈米零價鐵,生質能源 , spent mushroom substrate,Two-stage anaerobic digestion,Nanoscale Zero-Valent Iron,Bioenergy]

開發以生物碳與兩階段厭氧共消化之乾式厭氧發酵技術來轉換農業廢棄物為甲烷之研究 1100601~1110531 [乾式厭氧發酵,生物碳,甲烷 , Dry anaerobic fermentation,Biochar,Methane]

開發機能性有機蔬菜之發酵飲品 1090601~1100531 [發酵,十字花科,乳酸菌 , fermentation,Brassicaceae,lactic acid bacteria]

利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性 1080601~1090531 [山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]

藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究 1061101~1071031 [厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]

以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株 1060601~1070531 [巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]

「台灣化學工程學會63週年慶祝大會」、「科技部化學工程學門成果發表會 1051124~1051126

2016第21屆生物技術暨生物工程國際研討會 1050301~1050625

第21屆生物技術暨生物工程國際研討會 1050301~1050625

第21屆生物技術與生化工程年會 1050301~1050625

期刊著作

Improving bioactivities of Momordica charantia broth through fermentation using mixed cultures of Lactobacillus plantarum, Gluconacetobacter sp. and Saccharomyces cerevisiae Process Biochemistry, 117, 142-152, 2022-06-01 [ Charantin,Coumarin,Momordica charantia,Xanthine oxidase inhibition ]

Enhancing Methane Production in a Two-Stage Anaerobic Digestion of Spent Mushroom Substrate and Chicken Manure via Activation of Sludge, Optimization of Temperature, and C/N Ratio Frontiers in Environmental Science, 9, 2022-02-10

Temperature control and in situ product recovery strategies to enhance the bioconversion of L-phenylalanine into 2-phenylethanol Journal of Chemical Technology and Biotechnology, 2020-01-01 [ 2-phenylethanol,in situ product recovery,Saccharomyces cerevisiae,temperature control ]

Enhancing high quality oil accumulation and carbon dioxide fixation by a mixed culture of Chlorella sp. and Saccharomyces cerevisiae Journal of the Taiwan Institute of Chemical Engineers, 44, 6, 936-942, 2013-11-01 [ Carbon dioxide , Chlorella sp. , Mixed culture , Oil , Saccharomyces cerevisiae ]

Effects of light quality on the accumulation of oil in a mixed culture of Chlorella sp. and Saccharomyces cerevisiae Journal of Chemical Technology and Biotechnology, 87, 5, 601-607, 2012-05-01 [ Chlorella sp. , LED photo-bioreactor , Light quality , Lipid , Mixed-culture ]

Effects of aeration rate on the production of ergosterol and blazeispirol A by Agaricus blazei in batch cultures Journal of the Taiwan Institute of Chemical Engineers, 42, 2, 212-216, 2011-03-01 [ Aeration rate , Biochemical engineering , Bioprocesses , Fermentation ]

Effects of light intensity and light wavelength on the production of mycophenolic acid by Penicillium brevicompactum in batch cultures Enzyme and Microbial Technology, 46, 6, 466-471, 2010-05-01 [ Light intensity , Light wavelength , Mycophenolic acid , Penicillium brevicompactum ]

Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo Journal of Nutritional Biochemistry, 20, 10, 753-764, 2009-10-01 [ Agaricus blazei , Antitumor activity , Apoptosis , Human prostate cancer ]

Effects of light wavelength and intensity on the production of ethanol by Saccharomyces cerevisiae in batch cultures Journal of Chemical Technology and Biotechnology, 84, 8, 1156-1162, 2009-07-27 [ Ethanol , LED photo-bioreactor , Light intensity , Light wavelength , Saccharomyces cerevisiae ]

Biochemical properties and expression profile of human prolyl dipeptidase DPP9 Archives of Biochemistry and Biophysics, 485, 2, 120-127, 2009-05-15 [ Dimerization , Dipeptidyl peptidase , DPP9 , Substrate specificity ]

Enhanced removal of dimethyl sulfide from a synthetic waste gas stream using a bioreactor inoculated with Microbacterium sp. NTUT26 and Pseudomonas putida Journal of Industrial Microbiology and Biotechnology, 36, 1, 95-104, 2009-01-01 [ Biofiltration , Bioreactor , Dimethyl sulfide , Inoculation ]

Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged culture Journal of the Chinese Institute of Chemical Engineers, 39, 1, 1-8, 2008-01-01 [ Antioxidant , Antrodia camphorata , pH , Phenolics , Polyaccharide , Submerged fermentation ]

Production, purification and partial characterization of a novel endo-β-1,3-glucanase from Agaricus brasiliensis Process Biochemistry, 41, 5, 1229-1233, 2006-05-01 [ Agaricus brasiliensis , Characterization , Endo-β-1,3-glucanase , Exopolysaccharides , Purification , Thermostable ]

Purification and partial characterization of a lipase from Antrodia cinnamomea Process Biochemistry, 41, 3, 734-738, 2006-03-01 [ Antrodia cinnamomea , Lipase , Production , Purification ]

Effects of morphology and oxygen supply on schizophyllan formation by Schizophyllum commune using a pellet size controlling bioreactor Journal of Chemical Technology and Biotechnology, 80, 12, 1383-1388, 2005-01-01 [ Morphology , Pellet size control , Schizophyllan , Schizophyllum commune ]

Effects of culture pH on the production of bioactive polysaccharides by Agaricus blazei in batch cultures Journal of Chemical Technology and Biotechnology, 79, 9, 998-1002, 2004-09-01 [ β-glucan , Agaricus blazei , Molecular weight , pH , Polysaccharide , Tumor necrosis factor-α ]

Effect of pH on the production and molecular weight distribution of exopolysaccharide by Antrodia camphorata in batch cultures Process Biochemistry, 39, 8, 931-937, 2004-04-30 [ Antrodia camphorata , Exopolysaccharide , Molecular weight , pH , Submerged fermentation , Two-stage pH process ]

Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7. Biotechnology Letters, 26, 4, 2061-2064, 2004-01-01

Enhanced shear protection and increased production of an anti-tumor polysaccharide by Agaricus blazei in xanthan-supplemented cultures Biotechnology Letters, 25, 11, 873-876, 2003-06-01 [ Agaricus blazei , Anti-tumor polysaccharide , Shear protection , Stirred tank reactor , Xanthan ]

Effects of citric acid on cell growth and schizophyllan formation in the submerged culture of Schizophyllum commune Journal of the Chinese Institute of Chemical Engineers, 33, 3, 315-320, 2002-07-01 [ Citric acid , Kinetics , Schizophyllan , Schizophyllum commune ]

Optimization of L-phenylalanine production of Corynebacterium glutamicum under product feedback inhibition by elevated oxygen transfer rate Biotechnology and Bioengineering, 77, 2, 131-141, 2002-01-20 [ Corynebacterium glutamicum , Oxygen supply , Phenylalanine , Product inhibition ]

Kinetics and modeling of GM-CSF production by recombinant yeast in a three-phase fluidized bed bioreactor Biotechnology and Bioengineering, 53, 5, 470-477, 1997-03-05 [ fluidized bed bioreactor , kinetics , modeling , recombinant , yeast ]

Effect of particle loading on GM-CSF production by Saccharomyces cerevisiae in a three-phase fluidized bed bioreactor Biotechnology and Bioengineering, 51, 2, 229-236, 1996-07-20 [ bioreactor, fluidized bed , murine granulocyte-macrophage colony stimulating factor , Saccharomyces cerevisiae ]

Kinetics of continuous GM-CSF production by recombinant Saccharomyces cerevisiae in an airlift bioreactor Journal of Biotechnology, 48, 1-2, 107-116, 1996-07-18 [ Air-lift bioreactor , GM-CSF , Kinetics , Saccharomyces cerevisiae ]

Kinetics and stability of GM-CSF production by recombinant yeast cells immobilized in a fibrous-bed bioreactor Biotechnology Progress, 12, 4, 449-456, 1996-07-01

A substrate feeding strategy--using an oxystat for L-phenylalanine fermentation by Corynebacterium glutamicum Biotechnology Techniques, 8, 11, 843-846, 1994-11-01

Kinetics and modeling of temperature effects on batch xanthan gum fermentation Biotechnology and Bioengineering, 37, 6, 567-574, 1991-01-01 [ kinetics , model , temperature , xanthan fermentation ]

Effects of temperature on cell growth and xanthan production in batch cultures of Xanthomonas campestris Biotechnology and Bioengineering, 35, 5, 454-468, 1990-01-01

專書

Bioprocessing for Value-Added Products from Renewable Resources 447-463, 2007-12-01

開發混合特定功能菌株生產高GABA與低咖啡因之後發酵機能茶
1100801~1110731
[後發酵茶,γ-胺基丁酸,去咖啡因,乳酸菌,抗失眠 , post-fermentation tea,GABA,decaffeination,lactic acid bacteria,anti-insomnia]

開發以生物碳與兩階段厭氧共消化之乾式發酵技術來轉換農業廢棄物為甲烷之研究
1100601~1110531
[包木屑,兩階段厭氧消化,乾式發酵,共消化,生物炭 , spent mushroom substrate (SMS),two-stage anaerobic digestion,dry fermentation,co-digestion,biochar]

開發機能性有機蔬菜之發酵飲品
1090601~1100531
[十字花科,GABA,硫代葡萄糖苷（Glucosinolates）,活性發酵飲品,抗失眠,抗憂鬱 , Brassicaceae,GABA,Glucosinolates,functional vegetable juices,anti-insomnia,anti-depression]

利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性
1080601~1090531
[山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]

利用Cupriavidus necator轉化農業廢棄物中的木質素為香草酸之研究
1070801~1080731
[農業廢棄物,木質素,香草酸,鉤蟲貪銅菌 , Agricultural waste, lignin, vanillic acid, Cupriavidus necator]

藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究
1061101~1071031
[厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]

開發新型節能溫度感應海綿之萃取發酵於酵母菌生產香料苯乙醇之研究
1060801~1070731
[苯乙醇,萃取發酵,疏水PDMS 海綿,溫度感應,酵母菌 , 2-Phenylethanol, Saccharomyces cerevisiae, sponge extractive fermentation, temperature responsive]

以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株
1060601~1070531
[巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]

開發新型節能溫度感應疏水海棉之萃取式發酵槽於連續生產丁醇之研究
1050801~1060731
[疏水海綿, 萃取式發酵, 溫度感應高分子, 丁醇 , extractive fermentation, butanol, sponge, thermal responsive, poly-N-isopropylacrylamide]

開發新型疏水海綿萃取式發酵槽於發酵生產丁醇之研究
1040801~1050731
[extractive fermentation, butanol, sponge, PDMS ]

開發以奈米零價鐵於兩階段厭氧共消化技術轉化高固體菇包木屑廢棄物為氫氣與甲烷之研究
1120601~1130531
[菇包木屑,兩階段厭氧發酵,奈米零價鐵,生質能源 , spent mushroom substrate,Two-stage anaerobic digestion,Nanoscale Zero-Valent Iron,Bioenergy]

開發以生物碳與兩階段厭氧共消化之乾式厭氧發酵技術來轉換農業廢棄物為甲烷之研究
1100601~1110531
[乾式厭氧發酵,生物碳,甲烷 , Dry anaerobic fermentation,Biochar,Methane]

開發機能性有機蔬菜之發酵飲品
1090601~1100531
[發酵,十字花科,乳酸菌 , fermentation,Brassicaceae,lactic acid bacteria]

利用微生物發酵提升山苦瓜抗糖尿病及其他生物活性
1080601~1090531
[山苦瓜,抗糖尿病,發酵工程,Charantin , Momordica charantia,anti-diabetes,charantin,fermentation technology]

藉厭氧共消化技術轉化金針菇太空包木屑廢料與雞糞為沼氣之研究
1061101~1071031
[厭氧共消化,沼氣,金針菇太空包木屑廢料,雞糞 , Anaerobic co-digestion,methane,spent mushroom substrate,chicken droppings]

以發酵工程篩選出生產高抗癌成分之高溫巴西蘑菇菌株
1060601~1070531
[巴西蘑菇,發酵工程,抗癌多醣,blazeispirol A,高溫菌株 ]

「台灣化學工程學會63週年慶祝大會」、「科技部化學工程學門成果發表會
1051124~1051126

2016第21屆生物技術暨生物工程國際研討會
1050301~1050625

第21屆生物技術暨生物工程國際研討會
1050301~1050625

第21屆生物技術與生化工程年會
1050301~1050625

Improving bioactivities of Momordica charantia broth through fermentation using mixed cultures of Lactobacillus plantarum, Gluconacetobacter sp. and Saccharomyces cerevisiae
Process Biochemistry, 117, 142-152, 2022-06-01
[ Charantin,Coumarin,Momordica charantia,Xanthine oxidase inhibition ]

Enhancing Methane Production in a Two-Stage Anaerobic Digestion of Spent Mushroom Substrate and Chicken Manure via Activation of Sludge, Optimization of Temperature, and C/N Ratio
Frontiers in Environmental Science, 9, 2022-02-10

Temperature control and in situ product recovery strategies to enhance the bioconversion of L-phenylalanine into 2-phenylethanol
Journal of Chemical Technology and Biotechnology, 2020-01-01
[ 2-phenylethanol,in situ product recovery,Saccharomyces cerevisiae,temperature control ]

Enhancing high quality oil accumulation and carbon dioxide fixation by a mixed culture of Chlorella sp. and Saccharomyces cerevisiae
Journal of the Taiwan Institute of Chemical Engineers, 44, 6, 936-942, 2013-11-01
[ Carbon dioxide , Chlorella sp. , Mixed culture , Oil , Saccharomyces cerevisiae ]

Effects of light quality on the accumulation of oil in a mixed culture of Chlorella sp. and Saccharomyces cerevisiae
Journal of Chemical Technology and Biotechnology, 87, 5, 601-607, 2012-05-01
[ Chlorella sp. , LED photo-bioreactor , Light quality , Lipid , Mixed-culture ]

Effects of aeration rate on the production of ergosterol and blazeispirol A by Agaricus blazei in batch cultures
Journal of the Taiwan Institute of Chemical Engineers, 42, 2, 212-216, 2011-03-01
[ Aeration rate , Biochemical engineering , Bioprocesses , Fermentation ]

Effects of light intensity and light wavelength on the production of mycophenolic acid by Penicillium brevicompactum in batch cultures
Enzyme and Microbial Technology, 46, 6, 466-471, 2010-05-01
[ Light intensity , Light wavelength , Mycophenolic acid , Penicillium brevicompactum ]

Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo
Journal of Nutritional Biochemistry, 20, 10, 753-764, 2009-10-01
[ Agaricus blazei , Antitumor activity , Apoptosis , Human prostate cancer ]

Effects of light wavelength and intensity on the production of ethanol by Saccharomyces cerevisiae in batch cultures
Journal of Chemical Technology and Biotechnology, 84, 8, 1156-1162, 2009-07-27
[ Ethanol , LED photo-bioreactor , Light intensity , Light wavelength , Saccharomyces cerevisiae ]

Biochemical properties and expression profile of human prolyl dipeptidase DPP9
Archives of Biochemistry and Biophysics, 485, 2, 120-127, 2009-05-15
[ Dimerization , Dipeptidyl peptidase , DPP9 , Substrate specificity ]

Enhanced removal of dimethyl sulfide from a synthetic waste gas stream using a bioreactor inoculated with Microbacterium sp. NTUT26 and Pseudomonas putida
Journal of Industrial Microbiology and Biotechnology, 36, 1, 95-104, 2009-01-01
[ Biofiltration , Bioreactor , Dimethyl sulfide , Inoculation ]

Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged culture
Journal of the Chinese Institute of Chemical Engineers, 39, 1, 1-8, 2008-01-01
[ Antioxidant , Antrodia camphorata , pH , Phenolics , Polyaccharide , Submerged fermentation ]

Production, purification and partial characterization of a novel endo-β-1,3-glucanase from Agaricus brasiliensis
Process Biochemistry, 41, 5, 1229-1233, 2006-05-01
[ Agaricus brasiliensis , Characterization , Endo-β-1,3-glucanase , Exopolysaccharides , Purification , Thermostable ]

Purification and partial characterization of a lipase from Antrodia cinnamomea
Process Biochemistry, 41, 3, 734-738, 2006-03-01
[ Antrodia cinnamomea , Lipase , Production , Purification ]

Effects of morphology and oxygen supply on schizophyllan formation by Schizophyllum commune using a pellet size controlling bioreactor
Journal of Chemical Technology and Biotechnology, 80, 12, 1383-1388, 2005-01-01
[ Morphology , Pellet size control , Schizophyllan , Schizophyllum commune ]

Effects of culture pH on the production of bioactive polysaccharides by Agaricus blazei in batch cultures
Journal of Chemical Technology and Biotechnology, 79, 9, 998-1002, 2004-09-01
[ β-glucan , Agaricus blazei , Molecular weight , pH , Polysaccharide , Tumor necrosis factor-α ]

Effect of pH on the production and molecular weight distribution of exopolysaccharide by Antrodia camphorata in batch cultures
Process Biochemistry, 39, 8, 931-937, 2004-04-30
[ Antrodia camphorata , Exopolysaccharide , Molecular weight , pH , Submerged fermentation , Two-stage pH process ]

Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7.
Biotechnology Letters, 26, 4, 2061-2064, 2004-01-01

Enhanced shear protection and increased production of an anti-tumor polysaccharide by Agaricus blazei in xanthan-supplemented cultures
Biotechnology Letters, 25, 11, 873-876, 2003-06-01
[ Agaricus blazei , Anti-tumor polysaccharide , Shear protection , Stirred tank reactor , Xanthan ]

Effects of citric acid on cell growth and schizophyllan formation in the submerged culture of Schizophyllum commune
Journal of the Chinese Institute of Chemical Engineers, 33, 3, 315-320, 2002-07-01
[ Citric acid , Kinetics , Schizophyllan , Schizophyllum commune ]

Optimization of L-phenylalanine production of Corynebacterium glutamicum under product feedback inhibition by elevated oxygen transfer rate
Biotechnology and Bioengineering, 77, 2, 131-141, 2002-01-20
[ Corynebacterium glutamicum , Oxygen supply , Phenylalanine , Product inhibition ]

Kinetics and modeling of GM-CSF production by recombinant yeast in a three-phase fluidized bed bioreactor
Biotechnology and Bioengineering, 53, 5, 470-477, 1997-03-05
[ fluidized bed bioreactor , kinetics , modeling , recombinant , yeast ]

Effect of particle loading on GM-CSF production by Saccharomyces cerevisiae in a three-phase fluidized bed bioreactor
Biotechnology and Bioengineering, 51, 2, 229-236, 1996-07-20
[ bioreactor, fluidized bed , murine granulocyte-macrophage colony stimulating factor , Saccharomyces cerevisiae ]

Kinetics of continuous GM-CSF production by recombinant Saccharomyces cerevisiae in an airlift bioreactor
Journal of Biotechnology, 48, 1-2, 107-116, 1996-07-18
[ Air-lift bioreactor , GM-CSF , Kinetics , Saccharomyces cerevisiae ]

Kinetics and stability of GM-CSF production by recombinant yeast cells immobilized in a fibrous-bed bioreactor
Biotechnology Progress, 12, 4, 449-456, 1996-07-01

A substrate feeding strategy--using an oxystat for L-phenylalanine fermentation by Corynebacterium glutamicum
Biotechnology Techniques, 8, 11, 843-846, 1994-11-01

Kinetics and modeling of temperature effects on batch xanthan gum fermentation
Biotechnology and Bioengineering, 37, 6, 567-574, 1991-01-01
[ kinetics , model , temperature , xanthan fermentation ]

Effects of temperature on cell growth and xanthan production in batch cultures of Xanthomonas campestris
Biotechnology and Bioengineering, 35, 5, 454-468, 1990-01-01

Bioprocessing for Value-Added Products from Renewable Resources
447-463, 2007-12-01